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PEG 4 litres split
PEG 4 litres split is a bowel preparation solution that works by drawing water into the colon to cleanse it before a colonoscopy.
PEG 4 litres split is a bowel preparation solution that works by drawing water into the colon to cleanse it before a colonoscopy. Used for Bowel cleansing prior to colonoscopy.
At a glance
| Generic name | PEG 4 litres split |
|---|---|
| Also known as | SELG 1000 |
| Sponsor | European Institute of Oncology |
| Modality | Small molecule |
| Therapeutic area | Gastroenterology |
| Phase | Phase 3 |
Mechanism of action
It acts as an osmotic laxative, increasing the volume of fluid in the intestinal lumen, which helps to flush out the contents of the bowel, making it easier to visualize the colon during a procedure.
Approved indications
- Bowel cleansing prior to colonoscopy
Common side effects
- Nausea
- Abdominal cramping
Key clinical trials
- Effect of Probiotic on Gut Microbiome and Bacterial Translocation in Healthy Asian Volunteers (PHASE4)
- Bowel Cleansing for Colonoscopy: Comparison Between a Same Day Low-Volume Preparation and a Conventional 4L Split One (PHASE3)
- Single Dose Versus Split Dose Polyethylene Glycol-based Colonic Lavage for Colonoscopy (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |