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Oxycodone intravenously
Oxycodone binds to opioid receptors in the central nervous system to block pain signal transmission and produce analgesia.
Oxycodone binds to opioid receptors in the central nervous system to block pain signal transmission and produce analgesia. Used for Acute moderate to severe pain in hospitalized patients, Postoperative pain management.
At a glance
| Generic name | Oxycodone intravenously |
|---|---|
| Also known as | oxycodoneIV |
| Sponsor | Kuopio University Hospital |
| Drug class | Opioid analgesic |
| Target | Mu (μ) opioid receptor |
| Modality | Small molecule |
| Therapeutic area | Pain Management |
| Phase | FDA-approved |
Mechanism of action
Oxycodone is a semi-synthetic opioid agonist that acts primarily on mu (μ) opioid receptors in the brain and spinal cord. By binding to these receptors, it inhibits the release of neurotransmitters involved in pain perception and modulates pain signaling pathways. The intravenous formulation provides rapid onset of action for acute pain management in hospital settings.
Approved indications
- Acute moderate to severe pain in hospitalized patients
- Postoperative pain management
Common side effects
- Respiratory depression
- Nausea and vomiting
- Constipation
- Dizziness
- Pruritus
- Hypotension
- Sedation
Key clinical trials
- Opioid-Free Pain Control Regimen Following Robotic Radical Prostatectomy (PHASE2, PHASE3)
- Comparing the Safety and Effectiveness of Different Doses of Morphine Administered in Spinal Anethesia for Pain Relief After Hip Replacement Surgery (PHASE4)
- Clinical Study of Equivalent Doses of Oxycodone or Tegileridine on Patients Undergoing Gynecological Laparoscopic Hysterectomy (PHASE4)
- The Effect of Oliceridine Patient-Controlled Intravenous Analgesia on Postoperative Chronic Pain After Video-Assisted Thoracoscopic Lobectomy (PHASE4)
- Multimodal Analgesia Strategies After Major Shoulder Ambulatory Surgery (PHASE4)
- A Study on Oral and Intranasal Forms of Oxycodone in Healthy Volunteers Using Pharmacokinetic Modeling (PHASE1)
- NSAID Use After Robotic Partial Nephrectomy (PHASE2)
- Affective Effects of Pre-surgery Opioids: a Randomized, Doubleblind Placebo-controlled Trial (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Oxycodone intravenously CI brief — competitive landscape report
- Oxycodone intravenously updates RSS · CI watch RSS
- Kuopio University Hospital portfolio CI