Last reviewed · How we verify

Oxycodone DETERx

Collegium Pharmaceutical, Inc. · Phase 3 active Small molecule

Oxycodone DETERx is an extended-release formulation of oxycodone, a mu-opioid receptor agonist, designed with abuse-deterrent technology to reduce the potential for misuse.

Oxycodone DETERx is an extended-release formulation of oxycodone, a mu-opioid receptor agonist, designed with abuse-deterrent technology to reduce the potential for misuse. Used for Moderate to severe chronic pain requiring long-term opioid therapy.

At a glance

Generic nameOxycodone DETERx
SponsorCollegium Pharmaceutical, Inc.
Drug classOpioid analgesic (abuse-deterrent formulation)
TargetMu-opioid receptor
ModalitySmall molecule
Therapeutic areaPain Management
PhasePhase 3

Mechanism of action

Oxycodone DETERx combines the opioid analgesic oxycodone with Collegium's proprietary DETERx technology, which is intended to make the drug resistant to common methods of abuse such as crushing, chewing, or dissolving. The formulation maintains the pharmacological action of oxycodone—binding to mu-opioid receptors in the central nervous system to produce analgesia—while the abuse-deterrent coating aims to reduce diversion and misuse potential.

Approved indications

Common side effects

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape: