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Simpatol (oxedrine)
Simpatol (generic name: oxedrine) is a oxedrine drug. It is currently in unknown development for Eustachian Tube Congestion, Nasal congestion, Nasal discharge.
Simpatol works by binding to the Neuromedin-U receptor 2, which helps to regulate nasal and Eustachian tube function.
Simpatol is a small molecule with synonyms including ADVANTRA Z, ANALEPTIN, DL-SYNEPHRINE, ETHAPHENE, NSC-166285, and NSC-170956. It is a longer-acting adrenergic agent, similar to p-synephrine and m-synephrine, which are naturally occurring substances found in some plants and animals.
At a glance
| Generic name | oxedrine |
|---|---|
| Drug class | oxedrine |
| Target | Neuromedin-U receptor 2 |
| Therapeutic area | Neuroscience |
| Phase | unknown |
Mechanism of action
Think of it like a key fitting into a lock. Simpatol is the key that fits into the Neuromedin-U receptor 2 lock, which helps to turn off the signals that cause nasal congestion and Eustachian tube problems. This helps to relieve symptoms like stuffy nose and ear pressure.
Approved indications
- Eustachian Tube Congestion
- Nasal congestion
- Nasal discharge
Common side effects
Key clinical trials
- Vasoactive Drugs in Intensive Care Unit (PHASE4)
- Blood PREssure Augmentation in Large-vessel Occlusion Stroke Study (EARLY_PHASE1)
- Clinical Study of DA-007 for the Treatment of Chemotherapy Induced Alopecia (PHASE3)
- Sex Differences in Sympathetic Vascular Reactivity at High Altitude (NA)
- Study to Investigate the Effectiveness of a Topical Cosmetic Formulation DA-OTC-002 (NA)
- Sex Differences in Sympathetic Activity and Vascular Reactivity During Acute and Chronic Hypoxia. (NA)
- Intramuscular Phenylephrine HCL for Prevention of Spinal Anesthesia Induced Hypotension (PHASE4)
- Goal-Directed Intraoperative Fluid Management Using FloTrac© Monitoring in High-Risk Neurosurgical Patients (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Simpatol CI brief — competitive landscape report
- Simpatol updates RSS · CI watch RSS
- portfolio CI
Frequently asked questions about Simpatol
What is Simpatol?
How does Simpatol work?
What is Simpatol used for?
What is the generic name of Simpatol?
What drug class is Simpatol in?
What development phase is Simpatol in?
What does Simpatol target?
Related
- Drug class: All oxedrine drugs
- Target: All drugs targeting Neuromedin-U receptor 2
- Manufacturer: — full pipeline
- Therapeutic area: All drugs in Neuroscience
- Indication: Drugs for Eustachian Tube Congestion
- Indication: Drugs for Nasal congestion
- Indication: Drugs for Nasal discharge
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing