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Oral Suspending Vehicle
An oral suspending vehicle is a pharmaceutical formulation designed to keep solid drug particles uniformly dispersed in a liquid medium for oral administration.
At a glance
| Generic name | Oral Suspending Vehicle |
|---|---|
| Also known as | ORA-Plus® |
| Sponsor | McMaster University |
| Modality | Small molecule |
| Phase | FDA-approved |
Mechanism of action
Suspending vehicles are excipient-based liquid formulations that prevent drug particles from settling or aggregating, ensuring consistent dosing with each administration. They typically contain thickening agents, surfactants, and stabilizers to maintain uniform particle distribution and improve palatability and bioavailability of poorly soluble drugs.
Approved indications
Common side effects
Key clinical trials
- Melatonin for Treatment of Delirium in Critically Ill Adult Patients (PHASE2)
- Fecal Microbiota Transplantation for Primary Sclerosing Cholangitis - Randomized Study Versus Sham Transplantation (PHASE2)
- Efficacy, Safety, Tolerability, and Biomarker Effects of GT-02287 in Early Parkinson's Disease (PHASE2)
- Propranolol Treatment for Postoperative Chylothorax (PHASE1, PHASE2)
- Taurine Effect on Glycemic, Lipidic and Inflammatory Profile in Individuals With Type 2 Diabetes (PHASE2)
- Pharmacodynamic EffIcacy and Clinical Benefit of AT 007 in Patients With Sorbitol Dehydrogenase (SORD) Deficiency (PHASE2, PHASE3)
- A Study of How [14C]-BGB-16673 is Absorbed, Broken Down, and Removed From the Body After a Single Oral Dose in Healthy Participants (PHASE1)
- A Phase 2a Study to Evaluate ALS-008176 in the Virus Challenge Model (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Oral Suspending Vehicle CI brief — competitive landscape report
- Oral Suspending Vehicle updates RSS · CI watch RSS
- McMaster University portfolio CI