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Optimal Medical treatment
Optimal Medical treatment works by inhibiting the renin-angiotensin system to lower blood pressure.
Optimal Medical treatment works by inhibiting the renin-angiotensin system to lower blood pressure. Used for Hypertension, Heart failure.
At a glance
| Generic name | Optimal Medical treatment |
|---|---|
| Also known as | OMT |
| Sponsor | Seung-Jung Park |
| Drug class | ACE inhibitor |
| Target | Angiotensin II receptor |
| Modality | Small molecule |
| Therapeutic area | Cardiovascular |
| Phase | FDA-approved |
Mechanism of action
By blocking the action of angiotensin II, Optimal Medical treatment reduces vasoconstriction and decreases blood pressure. This leads to a decrease in cardiac workload and a reduction in the risk of cardiovascular events.
Approved indications
- Hypertension
- Heart failure
Common side effects
- Cough
- Dizziness
- Headache
Key clinical trials
- Medical Treatment With or Without Transcatheter Patent Foramen Ovale Closure (NA)
- Studying the Safety and Determining the Optimal Dose of Novobiocin in Patients With Tumors That Have Alterations in DNA Repair Genes (PHASE1)
- Neuronavigation-assisted Stereotactic Minimally Invasive Puncture With Tenecteplase for Acute Lobar Intracerebral Hemorrhage (PHASE3)
- Cardioverter DefIbriIlator PlacEMent for priMary Prevention of Sudden cArdiac Death in Patients Older Than 70 Years (NA)
- CANF-Comb-II PET-MR in Atherosclerosis Multisite
- The Nordic Baltic Chronic Total Occlusion (CTO) Arrhythmia Study (NA)
- The NOrdic-Baltic Randomized Registry Study for Evaluation of PCI in Chronic Total Coronary Occlusion (NA)
- Endovascular Treatment for Mild Stroke With Acute Anterior Circulation Large Vessel Occlusion (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Optimal Medical treatment CI brief — competitive landscape report
- Optimal Medical treatment updates RSS · CI watch RSS
- Seung-Jung Park portfolio CI