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Optifree Replenish
Optifree Replenish is a multi-purpose contact lens solution that cleans, disinfects, and conditions contact lenses through a combination of surfactants and antimicrobial agents.
Optifree Replenish is a multi-purpose contact lens solution that cleans, disinfects, and conditions contact lenses through a combination of surfactants and antimicrobial agents. Used for Contact lens cleaning, disinfection, and storage.
At a glance
| Generic name | Optifree Replenish |
|---|---|
| Sponsor | University of Waterloo |
| Modality | Small molecule |
| Therapeutic area | Ophthalmology |
| Phase | Phase 3 |
Mechanism of action
This solution uses a hydrogen peroxide-free formulation with surfactants to remove protein and lipid deposits from lens surfaces, while antimicrobial preservatives prevent microbial contamination. The solution also contains rewetting agents and electrolytes to maintain lens comfort and hydration throughout wear.
Approved indications
- Contact lens cleaning, disinfection, and storage
Common side effects
- Eye irritation
- Allergic reaction to preservatives
- Lens discomfort
Key clinical trials
- A Clinical Comparison of Marketed Lens Care Solutions With Avaira Lens Brand (NA)
- Ocular Responses to Short and Long-term Lens Wear (NA)
- Two Phase Clinical Study of the Impact of Contact Lenses and Solutions on Corneal Structure (NA)
- Clinical Study of Visibility Tinted Clariti Contact Lens (NA)
- The Physiological Consequence of Silicone-hydrogel Care-solution Bio-incompatibility (NA)
- Assessment of Tear Film-Based Proteins Associated With Care Solution Induced Corneal Staining (NA)
- Comparative Performance of a Bausch & Lomb Multipurpose Solution and Alcon OptiFree Replenish Multipurpose Solution (NA)
- Clinical Study of Clariti Monthly Contact Lens (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Optifree Replenish CI brief — competitive landscape report
- Optifree Replenish updates RSS · CI watch RSS
- University of Waterloo portfolio CI