Last reviewed · How we verify

NVA237 200 µg

Novartis · Phase 2 active Small molecule

NVA237 is a long-acting muscarinic antagonist that blocks the M3 muscarinic acetylcholine receptor in the airways, leading to bronchodilation.

NVA237 is a long-acting muscarinic antagonist that blocks the M3 muscarinic acetylcholine receptor in the airways, leading to bronchodilation. Used for Chronic obstructive pulmonary disease (COPD).

At a glance

Generic nameNVA237 200 µg
Also known asGlycopyrronium Bromide
SponsorNovartis
Drug classMuscarinic antagonist
TargetM3 muscarinic acetylcholine receptor
ModalitySmall molecule
Therapeutic areaRespiratory
PhasePhase 2

Mechanism of action

By blocking the M3 receptors, NVA237 reduces the constriction of the airways, which is beneficial in conditions such as chronic obstructive pulmonary disease (COPD).

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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