Last reviewed 2026-04-23 · How we verify

Nutritional supplements

Nutritional supplements provide essential vitamins, minerals, and other micronutrients to support normal physiological function and fill dietary gaps.

Nutritional supplements provide essential vitamins, minerals, and other micronutrients to support normal physiological function and fill dietary gaps. Used for Micronutrient deficiency prevention and treatment, General health maintenance and wellness.

At a glance

Mechanism of action

Nutritional supplements deliver concentrated forms of vitamins, minerals, amino acids, and other bioactive compounds that may be deficient in the diet. They work by replenishing micronutrient stores and supporting metabolic processes, immune function, and tissue maintenance. The specific mechanism depends on the individual nutrient or combination formulation.

Approved indications

• Micronutrient deficiency prevention and treatment
• General health maintenance and wellness

Common side effects

• Gastrointestinal upset
• Nausea
• Constipation or diarrhea

Key clinical trials

• The Effects of Resistance Training and a Plant-Based Supplement on Perimenopausal Symptoms and Muscle Health. (NA)
• Effects of Probiotics on Respiratory Tract Infections in Children: A Randomized, Placebo-Controlled Interventional Study (PHASE2)
• Probiotic Intervention Study (NA)
• ImmunoNutrition and Colorectal Adenocarcinoma Surgery - INCAS Study (NA)
• The Intervention of Obesity in Children With Prader-Willi Syndrome Using Prebiotics and Probiotics (NA)
• Effect of Nicotinamide Riboside on Ketosis, Fat Oxidation & Metabolic Rate (NA)
• Choline Supplementation and Cardiovascular Health (NA)
• Effects of 2-Aticyto Complex and D-Ribose on Pain and Clinical Course in Patients With Fibromyalgia (NA)

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.