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NSE dosage "normothermia arm"
NSE is a non-specific esterase that plays a role in cellular metabolism and stress response.
NSE is a non-specific esterase that plays a role in cellular metabolism and stress response. Used for Monitoring and management of conditions where cellular stress is a concern, such as stroke or traumatic brain injury.
At a glance
| Generic name | NSE dosage "normothermia arm" |
|---|---|
| Sponsor | Centre Hospitalier Departemental Vendee |
| Modality | Biologic |
| Therapeutic area | Neurology |
| Phase | Phase 3 |
Mechanism of action
NSE is involved in the breakdown of various cellular components, and its activity is often used as a marker of cellular damage or stress. In the context of normothermia, NSE may be used to monitor and manage conditions where cellular stress is a concern.
Approved indications
- Monitoring and management of conditions where cellular stress is a concern, such as stroke or traumatic brain injury
Common side effects
- Hypotension
- Bradycardia
- Increased risk of bleeding
Key clinical trials
- NSE Ancillary Study of The Therapeutic Hypothermia After Nonshockable Cardiac Arrest Trial. (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |