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NSE dosage "hypothermia arm"
NSE dosage "hypothermia arm" is a Biologic drug developed by Centre Hospitalier Departemental Vendee. It is currently in Phase 3 development for Neuroprotection in acute neurological injury (likely cardiac arrest, stroke, or traumatic brain injury) with therapeutic hypothermia.
NSE dosage in the hypothermia arm likely refers to a neuroprotective strategy using mild hypothermia to reduce neuronal injury during acute neurological events.
NSE dosage in the hypothermia arm likely refers to a neuroprotective strategy using mild hypothermia to reduce neuronal injury during acute neurological events. Used for Neuroprotection in acute neurological injury (likely cardiac arrest, stroke, or traumatic brain injury) with therapeutic hypothermia.
At a glance
| Generic name | NSE dosage "hypothermia arm" |
|---|---|
| Sponsor | Centre Hospitalier Departemental Vendee |
| Modality | Biologic |
| Therapeutic area | Neurology |
| Phase | Phase 3 |
Mechanism of action
Therapeutic hypothermia reduces cerebral metabolic rate and inflammation, potentially limiting ischemic or hypoxic brain damage. The 'hypothermia arm' designation suggests this is a comparative study arm testing NSE (neuron-specific enolase) dosing or monitoring in patients undergoing controlled temperature management. NSE itself is a biomarker of neuronal injury rather than a therapeutic agent.
Approved indications
- Neuroprotection in acute neurological injury (likely cardiac arrest, stroke, or traumatic brain injury) with therapeutic hypothermia
Common side effects
- Shivering and discomfort during cooling
- Coagulopathy and bleeding risk
- Infection risk
- Arrhythmias during rewarming
Key clinical trials
- NSE Ancillary Study of The Therapeutic Hypothermia After Nonshockable Cardiac Arrest Trial. (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- NSE dosage "hypothermia arm" CI brief — competitive landscape report
- NSE dosage "hypothermia arm" updates RSS · CI watch RSS
- Centre Hospitalier Departemental Vendee portfolio CI
Frequently asked questions about NSE dosage "hypothermia arm"
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Related
- Manufacturer: Centre Hospitalier Departemental Vendee — full pipeline
- Therapeutic area: All drugs in Neurology
- Indication: Drugs for Neuroprotection in acute neurological injury (likely cardiac arrest, stroke, or traumatic brain injury) with therapeutic hypothermia
- Compare: NSE dosage "hypothermia arm" vs similar drugs
- Pricing: NSE dosage "hypothermia arm" cost, discount & access