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Novel OPV2 candidate 2

Pierre Van Damme · Phase 2 active Biologic ✓ Verified May 2026

Novel OPV2 candidate 2 is a Biologic drug developed by Pierre Van Damme. It is currently in Phase 2 development.

A Phase II clinical trial (NCT04693286) is evaluating the safety and immunogenicity of a novel oral polio type 2 vaccine (nOPV2) in healthy newborns in Bangladesh. The vaccine is a protein-based candidate, also known as Phekellistatin 2, being studied for its potential to prevent poliomyelitis.

Likelihood of approval
15.3% vs 15.3% industry baseline
If approved by FDA: likely 2031–2034
Steps remaining: Phase 3 → NDA/BLA submission
Confidence: Medium
Why this estimate
  • Baseline phase 2 → approval rate +15.3pp
    Industry-wide phase 2 drugs reach approval ~15.3% of the time (BIO/Informa 2023 industry benchmark across all therapeutic areas).
Predicted approval windows by jurisdiction (conditional on FDA approval)
Regulator Country Likely year Lag vs FDA
FDA US 2031–2034
EMA EU 2032–2035 +0.7 yr
MHRA GB 2032–2035 +0.7 yr
Health Canada CA 2032–2036 +0.9 yr
TGA AU 2032–2036 +1.2 yr
PMDA JP 2032–2036 +1.5 yr
NMPA CN 2033–2037 +2.3 yr
MFDS KR 2032–2036 +1.4 yr
CDSCO IN 2032–2037 +1.8 yr
ANVISA BR 2033–2037 +2.3 yr

Hover any row for the lag rationale. Lag estimates are reduced when the drug has FDA Breakthrough or EMA PRIME designation (sponsors file globally in parallel).

Estimate based on the BIO/Informa industry phase transition rates plus per-drug modifiers for therapeutic area, sponsor type, FDA designations, mechanism, and trial design. Per-jurisdiction lags from Tufts CSDD international approval studies. Not investment, clinical or regulatory advice. Methodology: /methodology#likelihood.

At a glance

Generic nameNovel OPV2 candidate 2
SponsorPierre Van Damme
ModalityBiologic
PhasePhase 2

Approved indications

No approved indications tracked.

Common side effects

No common side effects on file.

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

Frequently asked questions about Novel OPV2 candidate 2

What is Novel OPV2 candidate 2?

Novel OPV2 candidate 2 is a Biologic drug developed by Pierre Van Damme.

Who makes Novel OPV2 candidate 2?

Novel OPV2 candidate 2 is developed by Pierre Van Damme (see full Pierre Van Damme pipeline at /company/pierre-van-damme).

What development phase is Novel OPV2 candidate 2 in?

Novel OPV2 candidate 2 is in Phase 2.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing