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no luteal support
no luteal support is a Small molecule drug developed by Dunamenti REK Istenhegyi IVF Center. It is currently FDA-approved for IVF cycle support (specific patient populations or cycle types as defined by Dunamenti REK Istenhegyi IVF Center).
This is a clinical protocol or treatment approach that deliberately omits luteal phase hormonal support following ovarian stimulation in assisted reproductive technology.
Researchers have studied the effect of luteal blood progesterone levels on ongoing pregnancy rates in IVF cycles with fresh blastocyst transfer. The studies involved analyzing progesterone levels in women undergoing IVF, but the findings do not provide conclusive evidence on the necessity of luteal support.
At a glance
| Generic name | no luteal support |
|---|---|
| Sponsor | Dunamenti REK Istenhegyi IVF Center |
| Modality | Small molecule |
| Therapeutic area | Reproductive Medicine / Fertility |
| Phase | FDA-approved |
Mechanism of action
In IVF cycles, luteal support typically involves administering progesterone or hCG after egg retrieval to support the corpus luteum and early pregnancy. This protocol intentionally foregoes such support, relying instead on endogenous hormone production or alternative approaches. The clinical rationale and outcomes of this approach would depend on specific patient selection and cycle characteristics.
Approved indications
- IVF cycle support (specific patient populations or cycle types as defined by Dunamenti REK Istenhegyi IVF Center)
Common side effects
Key clinical trials
- IVM - Fresh ET (THE SAIGON PROTOCOL) Versus IVF - FET in PCOS Women (NA)
- Letrozole-stimulated Cycle Strategy Versus Artificial Cycle Strategy (LETSACT) (NA)
- Is There a Need for Luteal Support in Modified Natural Cycle Frozen Embryo Transfer Cycles (PHASE4)
- Impact of IVF Hormonal Therapy on Endometrial Receptivity and Endometrial Senescent Cell Pathological Accumulation
- Pregnancy and Neonatal Follow-up of Ongoing Pregnancies Established in Clinical Trial P05787 (P05712)
- Follow-up Study of Frozen-thawed Embryo Transfer (FTET) Cycles After Cryopreservation of Embryos in Clinical Trial P05787 (P05716)
- Pregnancy and Neonatal Follow-up of Ongoing Pregnancies Established in Clinical Trial P05714 (Care Program)(P05715)
- An Open Labeled RCT on the Effect of Additional hCG Injection for LPS on Pregnancy Outcomes in IHH Patients (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- no luteal support CI brief — competitive landscape report
- no luteal support updates RSS · CI watch RSS
- Dunamenti REK Istenhegyi IVF Center portfolio CI
Frequently asked questions about no luteal support
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Related
- Manufacturer: Dunamenti REK Istenhegyi IVF Center — full pipeline
- Therapeutic area: All drugs in Reproductive Medicine / Fertility
- Indication: Drugs for IVF cycle support (specific patient populations or cycle types as defined by Dunamenti REK Istenhegyi IVF Center)
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing