Last reviewed · How we verify

NETILDEX™ eye drops solution

SIFI SpA · Phase 3 active Small molecule

NETILDEX combines netilmicin (an aminoglycoside antibiotic) with dexamethasone (a corticosteroid) to provide antimicrobial and anti-inflammatory effects in the eye.

NETILDEX combines netilmicin (an aminoglycoside antibiotic) with dexamethasone (a corticosteroid) to provide antimicrobial and anti-inflammatory effects in the eye. Used for Bacterial conjunctivitis with inflammation, Bacterial keratitis, Post-operative ocular inflammation and infection prophylaxis.

At a glance

Generic nameNETILDEX™ eye drops solution
SponsorSIFI SpA
Drug classAntibiotic/corticosteroid combination
TargetBacterial 30S ribosome (netilmicin); glucocorticoid receptor (dexamethasone)
ModalitySmall molecule
Therapeutic areaOphthalmology
PhasePhase 3

Mechanism of action

Netilmicin inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, providing broad-spectrum antibacterial coverage. Dexamethasone suppresses local inflammatory responses and immune-mediated tissue damage. Together, they address both infection and inflammation in ocular conditions.

Approved indications

Common side effects

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape: