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NETILDEX™ eye drops solution
NETILDEX combines netilmicin (an aminoglycoside antibiotic) with dexamethasone (a corticosteroid) to provide antimicrobial and anti-inflammatory effects in the eye.
NETILDEX combines netilmicin (an aminoglycoside antibiotic) with dexamethasone (a corticosteroid) to provide antimicrobial and anti-inflammatory effects in the eye. Used for Bacterial conjunctivitis with inflammation, Bacterial keratitis, Post-operative ocular inflammation and infection prophylaxis.
At a glance
| Generic name | NETILDEX™ eye drops solution |
|---|---|
| Sponsor | SIFI SpA |
| Drug class | Antibiotic/corticosteroid combination |
| Target | Bacterial 30S ribosome (netilmicin); glucocorticoid receptor (dexamethasone) |
| Modality | Small molecule |
| Therapeutic area | Ophthalmology |
| Phase | Phase 3 |
Mechanism of action
Netilmicin inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, providing broad-spectrum antibacterial coverage. Dexamethasone suppresses local inflammatory responses and immune-mediated tissue damage. Together, they address both infection and inflammation in ocular conditions.
Approved indications
- Bacterial conjunctivitis with inflammation
- Bacterial keratitis
- Post-operative ocular inflammation and infection prophylaxis
Common side effects
- Ocular irritation or discomfort
- Transient blurred vision
- Allergic conjunctivitis
- Increased intraocular pressure (with prolonged use)
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- NETILDEX™ eye drops solution CI brief — competitive landscape report
- NETILDEX™ eye drops solution updates RSS · CI watch RSS
- SIFI SpA portfolio CI