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Neo-Synalar Cream

Noah Rosenberg, MD · FDA-approved active Small molecule

Neo-Synalar Cream is a topical corticosteroid that reduces inflammation and suppresses immune responses in the skin.

Neo-Synalar Cream is a topical corticosteroid that reduces inflammation and suppresses immune responses in the skin. Used for Inflammatory and pruritic dermatoses responsive to topical corticosteroids (e.g., eczema, psoriasis, dermatitis).

At a glance

Generic nameNeo-Synalar Cream
Also known asNS 0.5%(0.35% neomycin base)/ FA 0.025% Cream
SponsorNoah Rosenberg, MD
Drug classTopical corticosteroid
TargetGlucocorticoid receptor
ModalitySmall molecule
Therapeutic areaDermatology
PhaseFDA-approved

Mechanism of action

The cream contains a potent corticosteroid (fluocinolone acetonide) that binds to glucocorticoid receptors in skin cells, suppressing inflammatory cytokine production and reducing vasodilation, edema, and pruritus. This makes it effective for inflammatory and allergic skin conditions where localized anti-inflammatory action is needed.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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