Last reviewed · How we verify
NaCl (Control)
NaCl (sodium chloride) is an inert saline solution used as a control comparator in clinical trials.
NaCl (sodium chloride) is an inert saline solution used as a control comparator in clinical trials. Used for Control arm in phase 3 clinical trial (Oslo University Hospital).
At a glance
| Generic name | NaCl (Control) |
|---|---|
| Also known as | NaCl |
| Sponsor | Oslo University Hospital |
| Modality | Small molecule |
| Phase | Phase 3 |
Mechanism of action
Sodium chloride is a physiologic salt solution that maintains osmotic balance and electrolyte homeostasis. In clinical trial contexts, it serves as a placebo or vehicle control to establish baseline safety and efficacy comparisons against active investigational agents. It has no pharmacologic mechanism of action beyond fluid and electrolyte replacement.
Approved indications
- Control arm in phase 3 clinical trial (Oslo University Hospital)
Common side effects
- Hypernatremia (with excessive administration)
- Fluid overload (with excessive administration)
- Local injection site reactions (if parenteral)
Key clinical trials
- Effect of Lidocaine Infusion Versus Dexmedemidine Infusion on the Neurocognitive Function of Elderly Patients Undergoing Endoscopic Retrograde Cholangiopancreatography(ERCP): a Randomized, Controlled Trial. (NA)
- A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia (PHASE3)
- Effects of Bronchial Segmental Endotoxin Instillation in Humans (PHASE2)
- A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma (PHASE2, PHASE3)
- Thumb Base Osteoarthritis: Ultrasound-guided Platelet-rich Plasma Versus Placebo Injection (PHASE2)
- MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM) (PHASE3)
- Repeated Bilateral Greater Occipital Nerve Blockade in Chronic Migraine and Chronic Tension-Type Headache (NA)
- Ultrasound-Guided Quadro-Iliac Plane Block for Pain Management After Total Hip Arthroplasty (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- NaCl (Control) CI brief — competitive landscape report
- NaCl (Control) updates RSS · CI watch RSS
- Oslo University Hospital portfolio CI