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NaCl
Sodium chloride (NaCl) is an electrolyte that restores and maintains normal sodium and chloride ion balance in the body.
Sodium chloride (NaCl) is an electrolyte that restores and maintains normal sodium and chloride ion balance in the body. Used for Sodium and chloride depletion, Hyponatremia, Dehydration.
At a glance
| Generic name | NaCl |
|---|---|
| Also known as | Placebo comparator, saline, sodium chloride, placebo, 3% sodium chloride injection |
| Sponsor | University Hospital, Limoges |
| Drug class | Electrolyte replacement |
| Modality | Small molecule |
| Therapeutic area | General/Supportive Care |
| Phase | FDA-approved |
Mechanism of action
NaCl dissociates into sodium and chloride ions, which are essential for maintaining osmotic pressure, fluid balance, nerve conduction, and muscle contraction. It is used as an intravenous or oral replacement therapy to correct electrolyte deficiencies and maintain homeostasis in various clinical conditions.
Approved indications
- Sodium and chloride depletion
- Hyponatremia
- Dehydration
- Maintenance of fluid and electrolyte balance
Common side effects
- Hypernatremia (with excessive administration)
- Fluid overload
- Hyperchloremia
- Phlebitis (with IV administration)
Key clinical trials
- Testing the Addition of a New Anti-Cancer Drug, Triapine, to the Usual Chemotherapy Treatment (Cisplatin) During Radiation Therapy for Advanced-stage Cervical and Vaginal Cancers (PHASE3)
- Testing the Addition of an Anti-cancer Drug, BAY 1895344, to the Usual Chemotherapy Treatment (Cisplatin, or Cisplatin and Gemcitabine) for Advanced Solid Tumors With Emphasis on Urothelial Cancer (PHASE1)
- Effect of Lidocaine Infusion Versus Dexmedemidine Infusion on the Neurocognitive Function of Elderly Patients Undergoing Endoscopic Retrograde Cholangiopancreatography(ERCP): a Randomized, Controlled Trial. (NA)
- A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia (PHASE3)
- Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer (PHASE3)
- PRP Injection Into the Sacroiliac Joint After Ipsilateral THA: Effects on Early Recovery and Function (SIJ-THA Randomized Trial) (NA)
- Pulse Glucocorticoid Therapy in Patients With ST-Segment Elevation Myocardial Infarction (PHASE2)
- Effects of Bronchial Segmental Endotoxin Instillation in Humans (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- NaCl CI brief — competitive landscape report
- NaCl updates RSS · CI watch RSS
- University Hospital, Limoges portfolio CI