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Mycophenolate mofetil therapy
Mycophenolate mofetil therapy is a Small molecule drug developed by National Medical Research Center for Children's Health, Russian Federation. It is currently FDA-approved.
Mycophenolate mofetil is a small molecule inhibitor of inosine-5'-monophosphate dehydrogenase (IMPDH), a type of enzyme. It is used as a maintenance immunosuppressive treatment for various conditions, including Type 1 Diabetes, Islet Transplantation, Primary Myelofibrosis, Secondary Myelofibrosis, and Rheumatoid Arthritis.
At a glance
| Generic name | Mycophenolate mofetil therapy |
|---|---|
| Sponsor | National Medical Research Center for Children's Health, Russian Federation |
| Modality | Small molecule |
| Phase | FDA-approved |
Approved indications
Common side effects
Key clinical trials
- Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies (PHASE2)
- Belimumab and Rituximab Combination Therapy for the Treatment of Diffuse Cutaneous Systemic Sclerosis (PHASE2)
- MT2025-35 Allogeneic Hematopoietic Stem Cell Transplantation Using Reduced Intensity Conditioning Treosulfan and Fludarabine, With Post-Transplant Cytoxan (PTCy) for the Treatment of Hematological Diseases (PHASE2)
- Therapeutic Drug Monitoring of Mycophenolate Mofetil in Lupus Nephritis (NA)
- Upfront Autologous HSCT Versus Immunosuppression in Early Diffuse Cutaneous Systemic Sclerosis (PHASE4)
- Allogeneic Hematopoietic Stem Cell Transplant for GATA2 Mutations (PHASE2)
- Assessment of Biomarker-Guided CNI Substitution In Kidney Transplantation (PHASE2)
- A Study to Evaluate Axatilimab Versus Best Available Therapy in Participants With Chronic Graft Versus Host Disease After at Least 2 Prior Lines of Systemic Therapy (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Mycophenolate mofetil therapy CI brief — competitive landscape report
- Mycophenolate mofetil therapy updates RSS · CI watch RSS
- National Medical Research Center for Children's Health, Russian Federation portfolio CI
Frequently asked questions about Mycophenolate mofetil therapy
What is Mycophenolate mofetil therapy?
Who makes Mycophenolate mofetil therapy?
What development phase is Mycophenolate mofetil therapy in?
Related
- Manufacturer: National Medical Research Center for Children's Health, Russian Federation — full pipeline
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing