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Multimodal Pain Regimen
A multimodal pain regimen combines multiple analgesic agents with different mechanisms of action to provide synergistic pain relief.
A multimodal pain regimen combines multiple analgesic agents with different mechanisms of action to provide synergistic pain relief. Used for Acute postoperative pain, Chronic pain conditions.
At a glance
| Generic name | Multimodal Pain Regimen |
|---|---|
| Sponsor | University of California, Los Angeles |
| Modality | Small molecule |
| Therapeutic area | Pain Management |
| Phase | FDA-approved |
Mechanism of action
This approach typically integrates medications from different drug classes (e.g., opioids, non-steroidal anti-inflammatory drugs, adjuvant analgesics, and/or regional anesthesia techniques) to target pain through multiple pathways simultaneously. By addressing nociceptive, neuropathic, and inflammatory components of pain concurrently, multimodal regimens aim to improve efficacy while potentially reducing individual drug doses and associated adverse effects.
Approved indications
- Acute postoperative pain
- Chronic pain conditions
Common side effects
- Nausea and vomiting
- Dizziness
- Sedation
- Constipation
Key clinical trials
- Examining Analgesic Synergy and Efficacy in Trauma Care (PHASE4)
- Continous Infusion of Nefopam for Patients Undergoing Pancreatoduodenectomy (PHASE4)
- Opioid Free and Opioid Based Anesthesia in Elective Lumbar Spine Surgery
- Visually Guided TAP Block in Laparoscopic TAPP Hernia Repair (NA)
- A Study on Reducing Opioid Use After Minimally Invasive Ankle Surgery (NA)
- Phase 2 Bunionectomy HTX-011 Administration Study (PHASE2)
- Phase 2 Herniorrhaphy Study for Opioid Elimination (PHASE2)
- Total Knee Arthroplasty (TKA) Study of HTX-011 in an Multimodal Analgesic Regimen (MMA) Regimen (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Multimodal Pain Regimen CI brief — competitive landscape report
- Multimodal Pain Regimen updates RSS · CI watch RSS
- University of California, Los Angeles portfolio CI