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MR13A9

Kissei Pharmaceutical Co., Ltd. · Phase 3 active Small molecule

MR13A9 is a selective sodium-glucose cotransporter 2 (SGLT2) inhibitor that reduces blood glucose by promoting urinary glucose excretion.

MR13A9 is a selective sodium-glucose cotransporter 2 (SGLT2) inhibitor that reduces blood glucose by promoting urinary glucose excretion. Used for Type 2 diabetes mellitus.

At a glance

Generic nameMR13A9
SponsorKissei Pharmaceutical Co., Ltd.
Drug classSGLT2 inhibitor
TargetSGLT2 (Sodium-Glucose Cotransporter 2)
ModalitySmall molecule
Therapeutic areaDiabetes
PhasePhase 3

Mechanism of action

SGLT2 inhibitors block the reabsorption of filtered glucose in the proximal tubule of the kidney, allowing excess glucose to be excreted in urine. This mechanism lowers blood glucose levels independently of insulin secretion and has additional cardiovascular and renal protective effects. MR13A9 is being developed as a treatment for type 2 diabetes and potentially other metabolic conditions.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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