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Moxifloxacin Injectable Product

Fundacion Clinic per a la Recerca Biomédica · FDA-approved active Small molecule

Moxifloxacin is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication and transcription.

Moxifloxacin is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication and transcription. Used for Bacterial infections (community-acquired pneumonia, complicated skin infections, intra-abdominal infections, acute bacterial sinusitis), Hospital-acquired pneumonia, Complicated urinary tract infections.

At a glance

Generic nameMoxifloxacin Injectable Product
SponsorFundacion Clinic per a la Recerca Biomédica
Drug classFluoroquinolone antibiotic
TargetDNA gyrase; Topoisomerase IV
ModalitySmall molecule
Therapeutic areaInfectious Disease
PhaseFDA-approved

Mechanism of action

Moxifloxacin binds to and inhibits DNA gyrase (in gram-negative bacteria) and topoisomerase IV (in gram-positive bacteria), enzymes essential for bacterial DNA replication and repair. This dual inhibition leads to rapid bactericidal activity against a broad spectrum of aerobic and anaerobic bacteria. The injectable formulation allows for systemic delivery in serious infections where oral administration is not feasible.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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