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moxifloxacin 0,5% + prednisolone 1%
moxifloxacin 0,5% + prednisolone 1% is a fluoroquinolone antibiotic and corticosteroid Small molecule drug developed by Adapt Produtos Oftalmológicos Ltda.. It is currently in Phase 3 development for Bacterial conjunctivitis, keratitis, and blepharitis. Also known as: moxifloxacin 0,5%, prednisolone 1%.
Moxifloxacin is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV, while prednisolone is a corticosteroid that reduces inflammation by inhibiting phospholipase A2 and other pro-inflammatory enzymes.
Moxifloxacin is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV, while prednisolone is a corticosteroid that reduces inflammation by inhibiting phospholipase A2 and other pro-inflammatory enzymes. Used for Bacterial conjunctivitis, keratitis, and blepharitis.
At a glance
| Generic name | moxifloxacin 0,5% + prednisolone 1% |
|---|---|
| Also known as | moxifloxacin 0,5%, prednisolone 1% |
| Sponsor | Adapt Produtos Oftalmológicos Ltda. |
| Drug class | fluoroquinolone antibiotic and corticosteroid |
| Target | DNA gyrase and topoisomerase IV, phospholipase A2 |
| Modality | Small molecule |
| Therapeutic area | Ophthalmology |
| Phase | Phase 3 |
Mechanism of action
Moxifloxacin's mechanism of action involves binding to the bacterial DNA gyrase and topoisomerase IV enzymes, thereby inhibiting bacterial DNA replication and transcription. Prednisolone, on the other hand, works by inhibiting the production of pro-inflammatory enzymes, such as phospholipase A2, which are involved in the inflammatory response.
Approved indications
- Bacterial conjunctivitis, keratitis, and blepharitis
Common side effects
- Increased intraocular pressure
- Cataract
- Glaucoma
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- moxifloxacin 0,5% + prednisolone 1% CI brief — competitive landscape report
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- Adapt Produtos Oftalmológicos Ltda. portfolio CI
Frequently asked questions about moxifloxacin 0,5% + prednisolone 1%
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Related
- Drug class: All fluoroquinolone antibiotic and corticosteroid drugs
- Target: All drugs targeting DNA gyrase and topoisomerase IV, phospholipase A2
- Manufacturer: Adapt Produtos Oftalmológicos Ltda. — full pipeline
- Therapeutic area: All drugs in Ophthalmology
- Indication: Drugs for Bacterial conjunctivitis, keratitis, and blepharitis
- Also known as: moxifloxacin 0,5%, prednisolone 1%
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