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Morphine IV (rescue)
Morphine binds to opioid receptors in the central nervous system to block pain signal transmission and provide analgesia.
Morphine binds to opioid receptors in the central nervous system to block pain signal transmission and provide analgesia. Used for Acute severe pain (rescue/breakthrough pain), Post-operative pain, Acute myocardial infarction-related pain.
At a glance
| Generic name | Morphine IV (rescue) |
|---|---|
| Also known as | Both groups received Morphine IV (rescue) |
| Sponsor | Hospital Central Dr. Luis Ortega |
| Drug class | Opioid analgesic |
| Target | Mu-opioid receptor (μ-OR) |
| Modality | Small molecule |
| Therapeutic area | Pain Management |
| Phase | FDA-approved |
Mechanism of action
Morphine is a mu-opioid receptor agonist that acts on opioid receptors in the brain and spinal cord to modulate pain perception and emotional response to pain. When administered intravenously as a rescue medication, it provides rapid onset analgesia for acute, severe pain. The drug also produces sedation and anxiolysis, making it suitable for acute pain management in hospital settings.
Approved indications
- Acute severe pain (rescue/breakthrough pain)
- Post-operative pain
- Acute myocardial infarction-related pain
Common side effects
- Respiratory depression
- Hypotension
- Nausea and vomiting
- Sedation
- Constipation
- Pruritus
- Dizziness
Key clinical trials
- Serratus Posterior Superior Plane Block for Postoperative Pain in Cardiac Surgery (NA)
- Multimodal Analgesia Effect on Post Surgical Patient (PHASE4)
- Bilateral Erector Spinae Plane Block for Postoperative Chronic Pain After Open Heart Surgery (NA)
- Modified Thoracoabdominal Nerve Plane Block In Living Liver Donors (NA)
- EOIB for Laparoscopic Cholecystectomy (NA)
- Does Type of Anesthesia Influence Inflammation Change After Breast Surgery? (NA)
- Effect of Ketorolac on Post Adenotonsillectomy Pain (PHASE4)
- Laparoscopic Sleeve Gastrectomy Surgery and External Oblique Intercostal Block (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Morphine IV (rescue) CI brief — competitive landscape report
- Morphine IV (rescue) updates RSS · CI watch RSS
- Hospital Central Dr. Luis Ortega portfolio CI