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Mometasone furoate as a nasal spray
Mometasone furoate as a nasal spray is a Intranasal corticosteroid Small molecule drug developed by Zheng Liu ENT. It is currently in Phase 3 development for Allergic rhinitis, Nasal polyps, Non-allergic rhinitis.
Mometasone furoate is a corticosteroid that reduces inflammation in the nasal passages by suppressing immune and inflammatory responses.
Mometasone furoate is a corticosteroid that reduces inflammation in the nasal passages by suppressing immune and inflammatory responses. Used for Allergic rhinitis, Nasal polyps, Non-allergic rhinitis.
At a glance
| Generic name | Mometasone furoate as a nasal spray |
|---|---|
| Sponsor | Zheng Liu ENT |
| Drug class | Intranasal corticosteroid |
| Target | Glucocorticoid receptor |
| Modality | Small molecule |
| Therapeutic area | Otolaryngology / Allergy |
| Phase | Phase 3 |
Mechanism of action
Mometasone furoate binds to glucocorticoid receptors in nasal tissue, inhibiting the production of pro-inflammatory cytokines and mediators. This reduces nasal inflammation, congestion, and associated symptoms in allergic and non-allergic rhinitis. The nasal spray formulation delivers the drug directly to the site of inflammation with minimal systemic absorption.
Approved indications
- Allergic rhinitis
- Nasal polyps
- Non-allergic rhinitis
Common side effects
- Headache
- Pharyngitis
- Epistaxis
- Nasal irritation
Key clinical trials
- A Extension Clinical Study of TQC2731 Injection in the Treatment of Chronic Sinusitis With Nasal Polyps (PHASE2)
- A Study of the Efficacy and Safety of Brensocatib in Participants With Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP) (PHASE2)
- Intranasal Steroid as Medical Therapy For Sleep-Disordered Breathing in Children (PHASE4)
- A Study to Evaluate the Efficacy and Safety of HTMC0658 Tablets in the Treatment of Chronic Rhinosinusitis Without Nasal Polyps (PHASE2)
- Vibroacoustic Therapy With Oscillating Positive Expiratory Pressure in the Treatment of Nasal Congestion (NA)
- A Clinical Study of TQC2731 Injection in the Treatment of Chronic Rhinosinusitis With Nasal Polyps (PHASE2)
- Equivalency Study of Two Formulations of Mometasone Furoate Nasal Spray (Study P04419) (PHASE3)
- Effectiveness and Safety of Once or Twice Daily Mometasone Nasal Spray Versus Amoxicillin Versus Placebo for Treatment of Acute Rhinosinusitis (Study P02683) (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Mometasone furoate as a nasal spray CI brief — competitive landscape report
- Mometasone furoate as a nasal spray updates RSS · CI watch RSS
- Zheng Liu ENT portfolio CI
Frequently asked questions about Mometasone furoate as a nasal spray
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Related
- Drug class: All Intranasal corticosteroid drugs
- Target: All drugs targeting Glucocorticoid receptor
- Manufacturer: Zheng Liu ENT — full pipeline
- Therapeutic area: All drugs in Otolaryngology / Allergy
- Indication: Drugs for Allergic rhinitis
- Indication: Drugs for Nasal polyps
- Indication: Drugs for Non-allergic rhinitis
- Compare: Mometasone furoate as a nasal spray vs similar drugs
- Pricing: Mometasone furoate as a nasal spray cost, discount & access