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Minoxidil lotion 1%
Minoxidil is a potassium channel opener that increases blood flow to hair follicles and prolongs the anagen (growth) phase of the hair cycle.
Minoxidil is a potassium channel opener that increases blood flow to hair follicles and prolongs the anagen (growth) phase of the hair cycle. Used for Androgenetic alopecia (male and female pattern hair loss).
At a glance
| Generic name | Minoxidil lotion 1% |
|---|---|
| Sponsor | Mae Fah Luang University Hospital |
| Drug class | Potassium channel opener / topical hair growth stimulant |
| Target | ATP-sensitive potassium channels |
| Modality | Small molecule |
| Therapeutic area | Dermatology |
| Phase | FDA-approved |
Mechanism of action
Minoxidil works by dilating blood vessels in the scalp, improving nutrient and oxygen delivery to hair follicles. It also directly stimulates hair follicle growth and extends the active growth phase, shifting hairs from telogen (resting) to anagen (growth) phase. The exact molecular mechanism remains incompletely understood, but vasodilation and direct follicle stimulation are the primary proposed mechanisms.
Approved indications
- Androgenetic alopecia (male and female pattern hair loss)
Common side effects
- Scalp irritation
- Dryness
- Itching
- Unwanted facial hair growth
- Contact dermatitis
Key clinical trials
- Efficacy and Safety of Finlândia Hair Lotion Association on Androgenetic Alopecia (PHASE3)
- N-Acetyl-Cysteine for Treatment of AGA in Men (PHASE4)
- Efficacy of Therapy With the Spironolactone Pills Compared to Minoxidil Lotion in Female Pattern Hair Loss (PHASE2)
- Minoxidil 1% for Eyebrow Enhancement (PHASE4)
- Minoxidil 2% for Eyebrow Enhancement (PHASE4)
- Efficacy Study of Minoxidil Lotion Versus Combined Minoxidil and Finasteride Lotion to Treat Male Pattern Hair Loss (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Minoxidil lotion 1% CI brief — competitive landscape report
- Minoxidil lotion 1% updates RSS · CI watch RSS
- Mae Fah Luang University Hospital portfolio CI