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MIC
MIC is a broad-spectrum antibiotic that inhibits cell wall synthesis by binding to the bacterial cell wall.
MIC is a broad-spectrum antibiotic that inhibits cell wall synthesis by binding to the bacterial cell wall. Used for Treatment of infections caused by susceptible bacteria, including pneumonia, skin and soft tissue infections, and urinary tract infections.
At a glance
| Generic name | MIC |
|---|---|
| Sponsor | TolerogenixX GmbH |
| Drug class | β-lactam antibiotic |
| Target | bacterial cell wall |
| Modality | Biologic |
| Therapeutic area | Infectious disease |
| Phase | FDA-approved |
Mechanism of action
MIC works by binding to the D-alanyl-D-alanine terminus of bacterial cell wall precursors, thereby inhibiting the action of bacterial transpeptidases and ultimately preventing the formation of the bacterial cell wall. This leads to cell lysis and death. MIC is effective against a wide range of Gram-positive and Gram-negative bacteria.
Approved indications
- Treatment of infections caused by susceptible bacteria, including pneumonia, skin and soft tissue infections, and urinary tract infections
Common side effects
- Allergic reactions
- Nausea and vomiting
- Diarrhea
- Abdominal pain
- Headache
Key clinical trials
- Total Intravenous and Balanced Anesthesia in Diabetic Patients Undergoing Video-Assisted Thoracoscopy (PHASE4)
- Performance of the Cardiac Microcurrent (C-MIC) System With a Less Invasively Placed Left Ventricular Lead (NA)
- Mannitol Versus Nitroglycerin for Kidney Injury Prevention in Robotic-assisted Radical Prostatectomy or Cystectomy (NA)
- Premedication in Children: a Clinical Trial Comparing Oral Ketamine and Oral Clonidine With Respect to Sedation Level and Opioid Consumption in Pediatrics Undergoing Elective Lower Abdominal Day-case Surgery. (NA)
- Investigating the Acceptance and Performance of Low Energy Audio Streaming in Nucleus 8 and Kanso 3 Sound Processors by Experienced Cochlear Implant Users (NA)
- Ultrasound Guided Quadratus Lumborum Block, Thoracolumbar Interfascial Plane Block, and Local Anesthetic Infiltration for Lumbar Spine Fixation (NA)
- Performance and Safety of the Cardiac Microcurrent Therapy System (NA)
- Dexamethasone vs Dexmedetomidine in Sphenopalatine Ganglion Block for Rhinoplasty Pain (PHASE1)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- MIC CI brief — competitive landscape report
- MIC updates RSS · CI watch RSS
- TolerogenixX GmbH portfolio CI