Last reviewed · How we verify
Posicor (MIBEFRADIL)
At a glance
| Generic name | MIBEFRADIL |
|---|---|
| Drug class | mibefradil |
| Target | Voltage-dependent T-type calcium channel subunit alpha-1I |
| Modality | Small molecule |
| Therapeutic area | Cardiovascular |
| Phase | FDA-approved |
| First approval | 1997 |
Approved indications
- Angina pectoris
- Hypertensive disorder
Common side effects
Drug interactions
- alfuzosin
- silodosin
- tamsulosin
- terfenadine
Key clinical trials
- Association of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers With Post-Stroke Pneumonia: A Real-World Retrospective Cohort Study
- TAU-2014-1: Mibefradil and Hypofractionated Re-Irradiation Therapy in Recurrent GBM (PHASE1)
- Mibefradil Dihydrochloride and Temozolomide in Treating Patients With Recurrent Glioma (PHASE1)
- Safety Study of Mibefradil When Given Four Times a Day in Healthy Volunteers (PHASE1)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| FDA label | Mechanism, indications, dosing, boxed warnings, drug interactions |
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
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