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methadone tablets
Methadone tablets work by activating the mu-opioid receptor in the brain, which helps to reduce withdrawal symptoms and alleviate pain.
Methadone tablets work by activating the mu-opioid receptor in the brain, which helps to reduce withdrawal symptoms and alleviate pain. Used for Chronic pain, Opioid use disorder.
At a glance
| Generic name | methadone tablets |
|---|---|
| Also known as | Mytedom |
| Sponsor | University of Sao Paulo |
| Drug class | opioid |
| Target | mu-opioid receptor |
| Modality | Small molecule |
| Therapeutic area | Pain management |
| Phase | Phase 3 |
Mechanism of action
Methadone tablets are a type of opioid medication that binds to the mu-opioid receptor, which is responsible for pain perception and reward processing in the brain. By activating this receptor, methadone helps to reduce the severity of withdrawal symptoms and alleviate chronic pain.
Approved indications
- Chronic pain
- Opioid use disorder
Common side effects
- Nausea
- Dizziness
- Constipation
- Vomiting
- Headache
Key clinical trials
- Efficacy and Safety of Sustained-release Dexamphetamine in Patients With Moderate to Severe Cocaine Use Disorder (PHASE2)
- A Proof of Concept, Phase 2, Double-blind, Randomized Trial With d-Methadone Product Versus Placebo (PHASE2)
- Office-based Methadone Versus Buprenorphine to Address Retention in Medication for Opioid Use Disorder Treatment. (PHASE4)
- Postoperative Oral Methadone After Major Spine Surgery; Safety, Feasibility and Efficacy in Prevention of Progression to Chronic Opioid Usage at 3 Months (PHASE2, PHASE3)
- A Study to Evaluate the Efficacy and Safety of REL-1017 As Adjunctive Treatment of Major Depressive Disorder (MDD) (PHASE3)
- Evaluating the Safety of Acute Baclofen in Methadone-maintained Individuals With Opiate Dependence. (PHASE4)
- A Trial of Directly Observed and Long-term Varenicline (PHASE4)
- Anti-retroviral Therapy, Medications for Opioid Use Disorder, Opioids and HIV Infection - Study 1 (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- methadone tablets CI brief — competitive landscape report
- methadone tablets updates RSS · CI watch RSS
- University of Sao Paulo portfolio CI