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Menopur®, Ferring
Menopur is a purified preparation of human menopausal gonadotropins (hMG) containing follicle-stimulating hormone (FSH) and luteinizing hormone (LH) that stimulates ovarian follicle development and hormone production.
Menopur is a purified preparation of human menopausal gonadotropins (hMG) containing follicle-stimulating hormone (FSH) and luteinizing hormone (LH) that stimulates ovarian follicle development and hormone production. Used for Controlled ovarian hyperstimulation in assisted reproductive technology (ART) cycles, Ovulation induction in anovulatory women.
At a glance
| Generic name | Menopur®, Ferring |
|---|---|
| Sponsor | Instituto Valenciano de Infertilidad, IVI VALENCIA |
| Drug class | Gonadotropin |
| Target | FSH receptor (FSHR) and LH receptor (LHCGR) |
| Modality | Small molecule |
| Therapeutic area | Reproductive Medicine / Fertility |
| Phase | FDA-approved |
Mechanism of action
Menopur contains equal amounts of FSH and LH extracted from the urine of postmenopausal women. FSH directly stimulates follicle growth and estrogen production in the ovaries, while LH supports follicle maturation and triggers ovulation. This combination mimics the natural hormonal environment needed for controlled ovarian stimulation in assisted reproductive procedures.
Approved indications
- Controlled ovarian hyperstimulation in assisted reproductive technology (ART) cycles
- Ovulation induction in anovulatory women
Common side effects
- Ovarian hyperstimulation syndrome (OHSS)
- Injection site reactions (pain, bruising, redness)
- Headache
- Abdominal pain or bloating
- Nausea
Key clinical trials
- Ovarian Hyperstimulation and Fibrin Clot Properties. (NA)
- Is in Vitro Maturation of Oocytes Influenced by the Origin of Gonadotropins Used in Maturation Medium: is There a Difference in Efficiency When Using Urinary Versus Recombinant Produced Follicle Stimulating Hormone and Human Chorionic Gonadotropin
- Corifollitropin Alpha and Ovarian Response (NA)
- The Influence of AMH on Ovarian Responsiveness to Ovulation Induction With GnRH in Women With PCOS
- Randomized Controlled Trial Comparing Embryonic Quality in rFSH Versus hMG in IVF Protocol With GnRH Antagonist (PHASE4)
- Comparing Highly Purified hMG With Recombinant FSH + Recombinant LH in Women Undergoing Intrauterine Insemination. (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |