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MeningitecTM

GlaxoSmithKline · Phase 3 active Biologic

Meningitec is a conjugate vaccine that stimulates the immune system to produce antibodies against meningococcal serogroup C polysaccharide capsule.

Meningitec is a conjugate vaccine that stimulates the immune system to produce antibodies against meningococcal serogroup C polysaccharide capsule. Used for Prevention of invasive meningococcal disease caused by Neisseria meningitidis serogroup C.

At a glance

Generic nameMeningitecTM
SponsorGlaxoSmithKline
Drug classConjugate vaccine
TargetMeningococcal serogroup C polysaccharide capsule
ModalityBiologic
Therapeutic areaImmunology / Infectious Disease
PhasePhase 3

Mechanism of action

The vaccine consists of meningococcal serogroup C polysaccharide conjugated to a protein carrier (tetanus toxoid), which enhances immunogenicity and T-cell dependent immune response. This conjugation allows for improved antibody production and immunological memory compared to unconjugated polysaccharide vaccines, providing protection against invasive meningococcal disease caused by serogroup C.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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