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MenC
MenC stimulates the immune system to produce antibodies against the capsular polysaccharide of Neisseria meningitidis serogroup C.
MenC, developed by Novartis Vaccines, is a vaccine designed to prevent meningococcal disease caused by Neisseria meningitidis serogroup C. The vaccine works by stimulating the immune system to produce antibodies against the bacterial capsular polysaccharide. Despite its efficacy, MenC does not have an FDA label, indicating it may be approved in other regions or used under specific circumstances. Common side effects include injection site reactions and mild fever. The vaccine is generally well-tolerated, but contraindications and precautions should be considered before administration.
At a glance
| Generic name | MenC |
|---|---|
| Sponsor | Novartis Vaccines |
| Drug class | Conjugate vaccine |
| Target | Capsular polysaccharide of Neisseria meningitidis serogroup C |
| Modality | Biologic |
| Therapeutic area | Immunology |
| Phase | FDA-approved |
Mechanism of action
The vaccine contains purified capsular polysaccharide from Neisseria meningitidis serogroup C, which acts as an antigen to elicit an immune response.
Approved indications
Common side effects
- Injection site pain
- Redness at injection site
- Swelling at injection site
- Fever (≥38°C)
Key clinical trials
- Vaccines Against Salmonella Typhi (PHASE2)
- Immunogenicity and Safety of an Investigational Quadrivalent Meningococcal Conjugate Vaccine in Toddlers (PHASE3)
- Adolescent MenACWY Booster Study (PHASE4)
- Baby Vaccine Study (Sched3) (PHASE2)
- Hepatitis B Vaccination in Infants (PHASE4)
- Response to GSK Biologicals' Tritanrix-HepB/Hib-MenAC Vacc (4th Dose) at 15-24m & Mencevax ACWY at 24-30m (PHASE3)
- Immunogenicity and Safety Study of GlaxoSmithKline Biologicals' GSK2202083A Vaccine Administered as a Booster Dose (PHASE2)
- Immunogenicity & Safety Study of Combined/Separate Vaccine(s) Against Common Diseases in Infants (2,4,6 Months of Age). (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- MenC CI brief — competitive landscape report
- MenC updates RSS · CI watch RSS
- Novartis Vaccines portfolio CI