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MEMANTINE HYDROCHLORIDE
MEMANTINE HYDROCHLORIDE is a drug. It is currently FDA-approved (first approved 2002).
Memantine hydrochloride is a medication used to treat conditions such as Alzheimer's Disease, Alzheimer Dementia, and Down Syndrome, as well as Parkinson Disease, based on clinical trials. It is a drug that has been studied in combination with SUVN-502, but its exact mechanism of action is not specified in the provided information.
At a glance
| Generic name | MEMANTINE HYDROCHLORIDE |
|---|---|
| Modality | Small molecule |
| Phase | FDA-approved |
| First approval | 2002 |
Approved indications
Common side effects
- Diarrhea
- Headache
- Dizziness
- Nausea
- Vomiting
- Anorexia
- Insomnia
- Muscle cramp
- Fatigue
- Ecchymosis
- Urinary tract infection
Serious adverse events
- Stevens-Johnson syndrome
- Acute renal failure
- Cardiac failure congestive
- Hepatitis
- Pancreatitis
- Pancytopenia
- Agranulocytosis
- Leukopenia
- Neutropenia
Key clinical trials
- Memantine +/- Raloxifene for Cognitive Preservation After Radiation Therapy to the Brain (PHASE2)
- Motor Neurone Disease - Systematic Multi-Arm Adaptive Randomised Trial (PHASE2, PHASE3)
- Pattern Separation in Major Depressive Disorder (PHASE1)
- Targeting Spreading Depolarization After Chronic Subdural Hematoma Surgery (TASD) (EARLY_PHASE1)
- Memantine for the Treatment of Social Deficits in Youth With Disorders of Impaired Social Interactions (PHASE3)
- Memory Avoidance Whole Brain Radiotherapy vs Hippocampal Avoidance Whole Brain Radiotherapy (Athena 2 Trial) (PHASE2)
- Satisfaction With Orodispersible vs Conventional Memantine in Moderate to Severe Alzheimer's Disease (PHASE4)
- Memantine for the Treatment of Cognitive Impairment in Systemic Lupus Erythematosus (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| FDA label | Mechanism, indications, dosing, boxed warnings, drug interactions |
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- MEMANTINE HYDROCHLORIDE CI brief — competitive landscape report
- MEMANTINE HYDROCHLORIDE updates RSS · CI watch RSS
Frequently asked questions about MEMANTINE HYDROCHLORIDE
What is MEMANTINE HYDROCHLORIDE?
When was MEMANTINE HYDROCHLORIDE approved?
What development phase is MEMANTINE HYDROCHLORIDE in?
What are the side effects of MEMANTINE HYDROCHLORIDE?
Related
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing