EMA — authorised 27 April 2026
- Application: EMEA/H/C/006496
- Marketing authorisation holder: X4 Pharmaceuticals GmbH
- Local brand name: Xolremdi
- Indication: Xolremdi is indicated in patients 12 years of age and older for the treatment of WHIM syndrome (warts, hypogammaglobulinemia, infections and myelokathexis) to increase the number of circulating mature neutrophils and lymphocytes.
- Pathway: exceptional circumstances, orphan
- Status: approved
The European Medicines Agency (EMA) approved Xolremdi for the treatment of WHIM syndrome in patients aged 12 years and older. WHIM syndrome is a rare condition characterised by warts, low levels of antibodies, frequent infections, and a reduction in neutrophils and lymphocytes. Xolremdi, developed by X4 Pharmaceuticals GmbH, aims to increase the number of circulating mature neutrophils and lymphocytes in these patients.