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Magnesium glycinate
Magnesium glycinate provides bioavailable magnesium ions chelated to the amino acid glycine, which are absorbed and utilized for cofactor roles in cellular metabolism and neuromuscular function.
Magnesium glycinate provides bioavailable magnesium bound to the amino acid glycine, which is absorbed in the intestine and acts as a cofactor for numerous enzymatic and physiological processes. Used for Magnesium deficiency / hypomagnesemia, Nutritional supplementation for general health and wellness.
At a glance
| Generic name | Magnesium glycinate |
|---|---|
| Sponsor | CMH Kharian Medical College |
| Drug class | Mineral supplement / Nutritional supplement |
| Modality | Small molecule |
| Therapeutic area | Nutritional supplementation |
| Phase | FDA-approved |
Mechanism of action
Magnesium is an essential mineral that acts as a cofactor for over 300 enzymatic reactions in the body, including energy production, protein synthesis, and neuromuscular transmission. The glycine chelation enhances intestinal absorption compared to inorganic magnesium salts. Once absorbed, magnesium ions support muscle relaxation, nervous system regulation, and metabolic homeostasis.
Approved indications
- Magnesium deficiency / hypomagnesemia
- Muscle cramps and spasms
- Sleep support
- Stress and anxiety management
Common side effects
- Diarrhea
- Nausea
- Abdominal cramping
Key clinical trials
- Precision-Based Magnesium Trial (NA)
- Effect of Magnesium Supplementation on Elevated Systolic Blood Pressure (NA)
- Magnesium Supplementation and Blood Pressure Reduction (NA)
- Comparative Efficacy of Magnesium Supplement and Melatonin Congener in Young Adults With Primary Insomnia (NA)
- A Study to Evaluate the Efficacy and Safety of Clear Skin Formula on Mitigating Mild to Moderate Non-cystic Acne (NA)
- Calcium: Magnesium Balance, Microbiota, and Necroptosis and Inflammation (NA)
- Magnesium Treatment on Vitamin D Metabolism in Participants Completed Personalized Prevention of Colorectal Cancer Trial (NA)
- Ancillary Study of Methylation Biomarkers in a Randomized Controlled Trial of a Personalized Prevention of Colorectal Cancer (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Magnesium glycinate CI brief — competitive landscape report
- Magnesium glycinate updates RSS · CI watch RSS
- CMH Kharian Medical College portfolio CI