Last reviewed 2026-04-22 · How we verify

Magnesium Citrate Oral Liquid Product

Magnesium citrate draws water into the intestinal lumen osmotically to promote bowel evacuation.

Magnesium citrate draws water into the intestinal lumen osmotically to promote bowel evacuation. Used for Bowel preparation prior to colonoscopy or other gastrointestinal procedures, Relief of occasional constipation.

At a glance

Mechanism of action

Magnesium citrate is an osmotic laxative that increases the osmotic pressure within the colon, drawing fluid into the intestinal tract and softening stool. This increased intestinal fluid volume stimulates peristalsis and promotes bowel movement. It is commonly used for bowel preparation prior to medical procedures and for relief of occasional constipation.

Approved indications

• Bowel preparation prior to colonoscopy or other gastrointestinal procedures
• Relief of occasional constipation

Common side effects

• Diarrhea
• Abdominal cramping
• Nausea
• Bloating

Key clinical trials

• Study to Investigate the Effect of Rocatinlimab (AMG 451) on the Pharmacokinetics of Multiple Cytochrome P450 (CYP450) Substrates in Participants With Moderate to Severe Atopic Dermatitis (EARLY_PHASE1)
• TES RCT Fleet Enema vs Oral Mechanical Bowel Prep (PHASE4)
• FMT for MDRO Colonization After Infection in Renal Transplant Recipients (PHASE1)
• Naloxegol to Prevent Lower Gastrointestinal Paralysis in Critically Ill Adults Administered Opioids (PHASE4)

Primary sources

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Competitive intelligence

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