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Lumacaftor, Ivacaftor Drug Combination
Lumacaftor, Ivacaftor Drug Combination is a Small molecule drug developed by Carmel Medical Center. It is currently in Phase 2 development. Also known as: Orkambi.
At a glance
| Generic name | Lumacaftor, Ivacaftor Drug Combination |
|---|---|
| Also known as | Orkambi |
| Sponsor | Carmel Medical Center |
| Modality | Small molecule |
| Phase | Phase 2 |
Approved indications
Common side effects
Key clinical trials
- Validation of Respiratory Epithelial Functional Assessment to Predict Clinical Efficacy of Orkambi®. (NA)
- Modulate-CF: Cystic Fibrosis Transmembrane Regulator (CFTR) Biomarker Study to Evaluate the Rescue of Mutant CFTR in Patients With Cystic Fibrosis Treated With CFTR-modulators
- Personalized Theratyping Trial (EARLY_PHASE1)
- Real-life Follow-up of Cystic Fibrosis Patients Treated With Ivacaftor+Lumacaftor (Orkambi*)
- Mutation-specific Therapy for the Long QT Syndrome (PHASE2)
- Long-term Safety of Lumacaftor/Ivacaftor in Participants With Cystic Fibrosis Who Are Homozygous for F508del and 12 to <24 Months of Age at Treatment Initiation (PHASE3)
- Combined Effect of CFTR Protein Modulator Drugs and Exercise in Cystic Fibrosis (NA)
- A Study to Explore the Impact of Lumacaftor/Ivacaftor on Disease Progression in Subjects Aged 2 Through 5 Years With Cystic Fibrosis, Homozygous for F508del (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Lumacaftor, Ivacaftor Drug Combination CI brief — competitive landscape report
- Lumacaftor, Ivacaftor Drug Combination updates RSS · CI watch RSS
- Carmel Medical Center portfolio CI
Frequently asked questions about Lumacaftor, Ivacaftor Drug Combination
What is Lumacaftor, Ivacaftor Drug Combination?
Lumacaftor, Ivacaftor Drug Combination is a Small molecule drug developed by Carmel Medical Center.
Who makes Lumacaftor, Ivacaftor Drug Combination?
Lumacaftor, Ivacaftor Drug Combination is developed by Carmel Medical Center (see full Carmel Medical Center pipeline at /company/carmel-medical-center).
Is Lumacaftor, Ivacaftor Drug Combination also known as anything else?
Lumacaftor, Ivacaftor Drug Combination is also known as Orkambi.
What development phase is Lumacaftor, Ivacaftor Drug Combination in?
Lumacaftor, Ivacaftor Drug Combination is in Phase 2.
Related
- Manufacturer: Carmel Medical Center — full pipeline
- Also known as: Orkambi
- Compare: Lumacaftor, Ivacaftor Drug Combination vs similar drugs
- Pricing: Lumacaftor, Ivacaftor Drug Combination cost, discount & access