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Lower albumin dosage
Lower albumin dosage is a Plasma protein / Volume expander Small molecule drug developed by Centro Medico Issemym. It is currently in Phase 3 development for Hypovolemia or plasma volume expansion in critical illness or surgery, Hypoalbuminemia in liver disease or malnutrition. Also known as: Lung ultrasound guided administration of albumin.
Lower albumin dosage reduces the amount of human serum albumin administered to patients, potentially minimizing exposure-related adverse effects while maintaining therapeutic benefit.
Lower albumin dosage reduces the amount of human serum albumin administered to patients, potentially minimizing exposure-related adverse effects while maintaining therapeutic benefit. Used for Hypovolemia or plasma volume expansion in critical illness or surgery, Hypoalbuminemia in liver disease or malnutrition.
At a glance
| Generic name | Lower albumin dosage |
|---|---|
| Also known as | Lung ultrasound guided administration of albumin |
| Sponsor | Centro Medico Issemym |
| Drug class | Plasma protein / Volume expander |
| Modality | Small molecule |
| Therapeutic area | Critical Care / Supportive Care |
| Phase | Phase 3 |
Mechanism of action
Albumin is a carrier protein used clinically for volume expansion, nutritional support, and drug delivery. Reducing the dosage lowers the total protein load administered intravenously, which may decrease the risk of hypervolemia, allergic reactions, and other albumin-related complications. This approach aims to optimize the risk-benefit profile in conditions where albumin therapy is indicated but high doses may be problematic.
Approved indications
- Hypovolemia or plasma volume expansion in critical illness or surgery
- Hypoalbuminemia in liver disease or malnutrition
Common side effects
- Hypervolemia / fluid overload
- Allergic reaction
- Fever
- Chills
Key clinical trials
- A Phase I/II Study of WJB001 Combination Therapy on Safety and Efficacy for Advanced Solid Tumors (PHASE1, PHASE2)
- ANO31905 in Combination With Chemotherapy for CLDN18.2-Positive Locally Advanced Unresectable or Metastatic Pancreatic Cancer (PHASE1, PHASE2)
- Treatment Optimization for Patients With Type 2 Diabetes Using Empagliflozin and Finerenone in a Remote Clinical Trial (PHASE4)
- Venous Congestion and Organ Dysfunction.
- A Single-center, Prospective, Two Cohort Study of Surufatinib Combined With AG or AG in the First-line Treatment of Locally Advanced or Metastatic Pancreatic Cancer (PHASE2)
- Lung Point of Care Ultrasound to Guide Albumin Administration in Cirrhosis (PHASE3)
- Chemotherapy and Locoregional Therapy Trial (Surgery or Radiation) for Patients With Head and Neck Cancer (PHASE2)
- Low-dose Albumin Infusion for the Prevention of Paracentesis Induced Circulatory Dysfunction (PICD), After Large Volume Paracentesis (LVP) in Decompensated Cirrhosis Liver. (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Lower albumin dosage CI brief — competitive landscape report
- Lower albumin dosage updates RSS · CI watch RSS
- Centro Medico Issemym portfolio CI
Frequently asked questions about Lower albumin dosage
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Related
- Drug class: All Plasma protein / Volume expander drugs
- Manufacturer: Centro Medico Issemym — full pipeline
- Therapeutic area: All drugs in Critical Care / Supportive Care
- Indication: Drugs for Hypovolemia or plasma volume expansion in critical illness or surgery
- Indication: Drugs for Hypoalbuminemia in liver disease or malnutrition
- Also known as: Lung ultrasound guided administration of albumin
- Compare: Lower albumin dosage vs similar drugs
- Pricing: Lower albumin dosage cost, discount & access