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low dose clonidine HCl sustained release
Clonidine HCl works by stimulating alpha-2 adrenergic receptors in the brain, which decreases sympathetic nervous system activity and lowers blood pressure.
Clonidine HCl works by stimulating alpha-2 adrenergic receptors in the brain, which decreases sympathetic nervous system activity and lowers blood pressure. Used for Hypertension.
At a glance
| Generic name | low dose clonidine HCl sustained release |
|---|---|
| Sponsor | Addrenex Pharmaceuticals, Inc. |
| Drug class | Central alpha-2 adrenergic agonist |
| Target | Alpha-2 adrenergic receptor |
| Modality | Small molecule |
| Therapeutic area | Cardiovascular |
| Phase | Phase 3 |
Mechanism of action
This results in decreased peripheral vascular resistance and heart rate, leading to a decrease in blood pressure. Clonidine HCl also has a sedative effect, which can be beneficial in treating hypertension.
Approved indications
- Hypertension
Common side effects
- Dry mouth
- Dizziness
- Fatigue
- Headache
- Nausea
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
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