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Lopinavir-Monotherapy
Lopinavir-Monotherapy is a Small molecule drug developed by Cantonal Hospital of St. Gallen. It is currently FDA-approved. Also known as: Kaletra.
Lopinavir monotherapy is used to treat HIV infection. It is compared to triple therapy with a boosted protease inhibitor in terms of quality of life for HIV-positive patients.
At a glance
| Generic name | Lopinavir-Monotherapy |
|---|---|
| Also known as | Kaletra |
| Sponsor | Cantonal Hospital of St. Gallen |
| Modality | Small molecule |
| Phase | FDA-approved |
Approved indications
Common side effects
Key clinical trials
- Treatment of HIV/HCV Coinfection With Peg-IFN and Ribavirin in Patients Receiving ART Monotherapy With Lopinavir/r (PHASE4)
- Impact of Raltegravir Intensification on HIV-1-infected Subjects With Complete Viral Suppression Under Monotherapy With Protease Inhibitors (PHASE3)
- Second-line Therapy Antiretroviral in Patients Who Failed Non-nucleoside Reverse Transcriptase Inhibitor (NNRTI) - Based Regimens (PHASE4)
- Study to Compare the Virologic Efficacy in Cerebrospinal Fluid (CSF) and Neurocognitive State in Patients Infected by HIV-1 Long-term Treatment (> 3 Years) With Lopinavir / Ritonavir Monotherapy (PHASE4)
- Efficacy and Safety Study of Darunavir for the Treatment of HIV/AIDS (PHASE3)
- Safety and Tolerability Study to Evaluate Lower Dose of GSK2248761 in Antiretroviral Treatment-Naive HIV-1 Infected Adults. (PHASE2)
- HIV - Monotherapy in Switzerland (MOST-ch) (PHASE4)
- Safety and Effectiveness of Lopinavir/Ritonavir in Individuals Who Have Failed Prior HIV Therapy (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Lopinavir-Monotherapy CI brief — competitive landscape report
- Lopinavir-Monotherapy updates RSS · CI watch RSS
- Cantonal Hospital of St. Gallen portfolio CI
Frequently asked questions about Lopinavir-Monotherapy
What is Lopinavir-Monotherapy?
Who makes Lopinavir-Monotherapy?
Is Lopinavir-Monotherapy also known as anything else?
What development phase is Lopinavir-Monotherapy in?
Related
- Manufacturer: Cantonal Hospital of St. Gallen — full pipeline
- Also known as: Kaletra
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing