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local mometasone furoate treatment
local mometasone furoate treatment is a Topical corticosteroid Small molecule drug developed by University Hospital, Ghent. It is currently FDA-approved for Inflammatory skin conditions (e.g., eczema, dermatitis, psoriasis), Allergic skin reactions, Pruritus and other localized inflammatory dermatological conditions.
Mometasone furoate is a topical corticosteroid that suppresses local inflammatory and immune responses by binding to glucocorticoid receptors.
Mometasone furoate is a topical corticosteroid that suppresses local inflammatory and immune responses by binding to glucocorticoid receptors. Used for Inflammatory skin conditions (e.g., eczema, dermatitis, psoriasis), Allergic skin reactions, Pruritus and other localized inflammatory dermatological conditions.
At a glance
| Generic name | local mometasone furoate treatment |
|---|---|
| Sponsor | University Hospital, Ghent |
| Drug class | Topical corticosteroid |
| Target | Glucocorticoid receptor |
| Modality | Small molecule |
| Therapeutic area | Dermatology / Immunology |
| Phase | FDA-approved |
Mechanism of action
Mometasone furoate is a potent synthetic corticosteroid that reduces inflammation, itching, and immune-mediated reactions at the site of application. It works by activating glucocorticoid receptors in immune cells and epithelial tissues, leading to decreased production of inflammatory mediators and reduced recruitment of immune cells. When applied locally, it provides anti-inflammatory and antipruritic effects with minimal systemic absorption.
Approved indications
- Inflammatory skin conditions (e.g., eczema, dermatitis, psoriasis)
- Allergic skin reactions
- Pruritus and other localized inflammatory dermatological conditions
Common side effects
- Local skin atrophy
- Skin irritation or burning
- Folliculitis
- Hypopigmentation
Key clinical trials
- A Study of the Efficacy and Safety of Brensocatib in Participants With Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP) (PHASE2)
- A Study to Evaluate the Efficacy and Safety of HTMC0658 Tablets in the Treatment of Chronic Rhinosinusitis Without Nasal Polyps (PHASE2)
- A 24-week Prospective, Open-label, Multicenter, Single-arm rPMS Study in Real-world Setting for Atectura®
- A 24-week rPMS Study in Real-world Setting for Enerzair
- Vitiligo and the Koebner Phenomenon (Model of Vitiligo Induction and Therapy: a Clinical and Immunological Analysis) (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- local mometasone furoate treatment CI brief — competitive landscape report
- local mometasone furoate treatment updates RSS · CI watch RSS
- University Hospital, Ghent portfolio CI
Frequently asked questions about local mometasone furoate treatment
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Related
- Drug class: All Topical corticosteroid drugs
- Target: All drugs targeting Glucocorticoid receptor
- Manufacturer: University Hospital, Ghent — full pipeline
- Therapeutic area: All drugs in Dermatology / Immunology
- Indication: Drugs for Inflammatory skin conditions (e.g., eczema, dermatitis, psoriasis)
- Indication: Drugs for Allergic skin reactions
- Indication: Drugs for Pruritus and other localized inflammatory dermatological conditions
- Compare: local mometasone furoate treatment vs similar drugs
- Pricing: local mometasone furoate treatment cost, discount & access