Last reviewed 2026-04-20 · How we verify

Lipiodol

At a glance

Approved indications

No approved indications tracked.

Boxed warnings

• WARNING: FOR INTRALYMPHATIC, INTRAUTERINE AND SELECTIVE HEPATIC INTRA-ARTERIAL USE ONLY Pulmonary and cerebral embolism can result from inadvertent intravascular injection or intravasation of Lipiodol. Inject Lipiodol slowly with radiologic monitoring; do not exceed recommended dose ( 5.1 ). WARNING: FOR INTRALYMPHATIC, INTRAUTERINE AND SELECTIVE HEPATIC INTRA-ARTERIAL USE ONLY See Full Prescribing Information for complete Boxed Warning Pulmonary and cerebral embolism can result from inadvertent

Common side effects

• Abdominal pain
• Nausea
• Vomiting
• Fever
• Pain
• Dyspnea
• Cough
• Headache
• Skin rash
• Edema

Serious adverse events

• Pulmonary embolism
• Cerebral embolism
• Hypersensitivity reactions
• Anaphylactic reaction
• Anaphylactoid reaction
• Acute respiratory distress syndrome
• Hepatic vein thrombosis
• Liver decompensation
• Retinal vein thrombosis
• Thyroid dysfunction

Key clinical trials

• Prevention of Variceal Rebleeding by EUS-guided vs Conventional Endoscopic Therapy in Hepatocellular Carcinoma Patients (NA)
• Selective Internal Radiation Therapy and 188Re-SSS Lipiodol Treatment for Liver Cancer (Lip-Re2) (PHASE2)
• Safety and Efficacy of LVD + C-TACE + Tis/Len for Unresectable Right-Liver HCC (NA)
• Achilles Tendinopathy Embolization (PHASE1)
• Phase II Trial of Lung Chemoemobolization (PHASE2)
• MANDARIN (S6371) (PHASE3)
• CECT Features of MVI Predict Response to TACE Plus TKI in Intermediate-stage HCC
• Lateral Plantar Artery Embolization For Plantar Fasciitis (PHASE1)

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.