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Corflazine (LIDOFLAZINE)

Phase 2 active Small molecule

Corflazine (generic name: LIDOFLAZINE) is a lidoflazine drug. It is currently in Phase 2 development.

Corflazine works by blocking potassium channels in the body, which helps to regulate the electrical activity of cells.

Corflazine, also known as LIDOFLAZINE, is a small molecule drug that targets the potassium voltage-gated channel subfamily H member 2. It is classified as a lidoflazine drug and works by modulating ion channels to affect cellular excitability. However, due to the lack of available information, its commercial status, approved indications, half-life, bioavailability, and generic manufacturers are unknown. As a result, its FDA approval status and off-patent status also remain unclear. Further research is necessary to fully understand the properties and applications of Corflazine.

Likelihood of approval
15.3% vs 15.3% industry baseline
If approved by FDA: likely 2031–2034
Steps remaining: Phase 3 → NDA/BLA submission
Confidence: Medium
Why this estimate
  • Baseline phase 2 → approval rate +15.3pp
    Industry-wide phase 2 drugs reach approval ~15.3% of the time (BIO/Informa 2023 industry benchmark across all therapeutic areas).
Predicted approval windows by jurisdiction (conditional on FDA approval)
Regulator Country Likely year Lag vs FDA
FDA US 2031–2034
EMA EU 2032–2035 +0.7 yr
MHRA GB 2032–2035 +0.7 yr
Health Canada CA 2032–2036 +0.9 yr
TGA AU 2032–2036 +1.2 yr
PMDA JP 2032–2036 +1.5 yr
NMPA CN 2033–2037 +2.3 yr
MFDS KR 2032–2036 +1.4 yr
CDSCO IN 2032–2037 +1.8 yr
ANVISA BR 2033–2037 +2.3 yr

Hover any row for the lag rationale. Lag estimates are reduced when the drug has FDA Breakthrough or EMA PRIME designation (sponsors file globally in parallel).

Estimate based on the BIO/Informa industry phase transition rates plus per-drug modifiers for therapeutic area, sponsor type, FDA designations, mechanism, and trial design. Per-jurisdiction lags from Tufts CSDD international approval studies. Not investment, clinical or regulatory advice. Methodology: /methodology#likelihood.

At a glance

Generic nameLIDOFLAZINE
Drug classlidoflazine
TargetEquilibrative nucleoside transporter 1, Potassium voltage-gated channel subfamily H member 2, Sodium channel alpha subunits; brain (Types I, II, III)
ModalitySmall molecule
Therapeutic areaOther
PhasePhase 2

Mechanism of action

Think of your body's cells like tiny electrical circuits. Potassium channels help control the flow of electrical signals within these circuits. By blocking these channels, Corflazine helps to slow down the electrical activity of cells, which can be beneficial in certain medical conditions.

Approved indications

No approved indications tracked.

Common side effects

No common side effects on file.

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

Frequently asked questions about Corflazine

What is Corflazine?

Corflazine (LIDOFLAZINE) is a lidoflazine drug.

How does Corflazine work?

Corflazine works by blocking potassium channels in the body, which helps to regulate the electrical activity of cells.

What is the generic name of Corflazine?

LIDOFLAZINE is the generic (nonproprietary) name of Corflazine.

What drug class is Corflazine in?

Corflazine belongs to the lidoflazine class. See all lidoflazine drugs at /class/lidoflazine.

What development phase is Corflazine in?

Corflazine is in Phase 2.

What does Corflazine target?

Corflazine targets Equilibrative nucleoside transporter 1, Potassium voltage-gated channel subfamily H member 2, Sodium channel alpha subunits; brain (Types I, II, III) and is a lidoflazine.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing