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lidocaine treatment
Lidocaine blocks sodium channels in nerve cells, preventing the initiation and transmission of nerve impulses.
Lidocaine blocks sodium channels in nerve cells, preventing the initiation and transmission of nerve impulses. Used for Local anesthesia for minor surgical procedures, Treatment of ventricular arrhythmias.
At a glance
| Generic name | lidocaine treatment |
|---|---|
| Sponsor | Centre Hospitalier Universitaire, Amiens |
| Drug class | Local anesthetic |
| Target | Voltage-gated sodium channels |
| Modality | Small molecule |
| Therapeutic area | Cardiovascular |
| Phase | Phase 3 |
Mechanism of action
This action results in a reduction of the excitability of the nerve membrane, which in turn leads to a decrease in the release of pain-causing chemicals. Lidocaine's mechanism of action is primarily through its ability to bind to and block the sodium channels, preventing the rapid depolarization of the nerve membrane.
Approved indications
- Local anesthesia for minor surgical procedures
- Treatment of ventricular arrhythmias
Common side effects
- Central nervous system depression
- Allergic reactions
Key clinical trials
- OMT for Adhesive Capsulitis (PHASE4)
- Sphenopalatine Ganglion Block for Post-Dural Puncture Headache: A Pilot Randomised Controlled Trial (NA)
- The Analgesic Efficacy and Safety of Venlafaxine for Prevention of Postherpetic Neuralgia in Patients With Acute Herpes Zoster (NA)
- Jaw Muscle Pain Post Wisdom Molar Surgery (PHASE2)
- Comparison of the Effectiveness of Exercise, Dry Needling and Interfascial Block Treatments in the Treatment of Myofascial Pain Syndrome (NA)
- Continous Infusion of Nefopam for Patients Undergoing Pancreatoduodenectomy (PHASE4)
- ONC-MM-2407: The Effect of Virtual Reality Headsets on Pain and Anxiety in the Peri and Post Bone Marrow Biopsy Period (NA)
- Bladder Directed vs. Pelvic Floor Therapy in IC/BPS (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- lidocaine treatment CI brief — competitive landscape report
- lidocaine treatment updates RSS · CI watch RSS
- Centre Hospitalier Universitaire, Amiens portfolio CI