Last reviewed · How we verify
Lidocaine jelly application
Lidocaine jelly is a topical local anesthetic that blocks sodium channels in nerve cell membranes to prevent pain signal transmission.
Lidocaine jelly is a topical local anesthetic that blocks sodium channels in nerve cell membranes to prevent pain signal transmission. Used for Topical anesthesia for minor procedures and pain relief, Urological procedures, Wound care and minor surgical applications.
At a glance
| Generic name | Lidocaine jelly application |
|---|---|
| Sponsor | Keimyung University Dongsan Medical Center |
| Drug class | Local anesthetic |
| Target | Voltage-gated sodium channels |
| Modality | Small molecule |
| Therapeutic area | Pain management / Anesthesia |
| Phase | FDA-approved |
Mechanism of action
Lidocaine is an amide-type local anesthetic that reversibly inhibits sodium influx into nerve fibers, thereby preventing depolarization and conduction of action potentials. When applied as a jelly formulation, it provides localized anesthesia at the site of application, numbing tissues without systemic absorption when used appropriately. This allows for pain-free procedures or relief of localized pain and discomfort.
Approved indications
- Topical anesthesia for minor procedures and pain relief
- Urological procedures
- Mucosal surface anesthesia
Common side effects
- Local irritation or burning at application site
- Allergic contact dermatitis
- Systemic toxicity (rare, with excessive absorption)
Key clinical trials
- Pain Experience Using Lidocaine Adrenaline Tetracaine (LAT) Gel Versus Lidocaine Infiltration for Laceration Repair in Adults (PHASE4)
- This Clinical Trial Aims to Compare the Effectiveness of Two Intra-pulpal Cryotherapy Techniques-Endo-ice and Ice Sticks-in Decreasing Intra-operative Pain and Enhancing the Success of Local Anesthesia During Pulpectomy of Mandibular Molars With Symptomatic Irreversible Pulpitis. (NA)
- Pain Control for Cervical Ripening Balloon (PHASE2)
- The Use of Lidocaine Gel Versus Subconjunctival Xylocaine Injection in Pterygium Excision (PHASE4)
- Effectiveness of Needle-Free Infiltration Anesthesia in Reduction of Dental Pain and Anxiety During Local Anesthesia. (NA)
- Cryotherapy as a Topical Anesthetic in Healthy Children (PHASE4)
- Different Transcutaneous Electrical Nerve Stimulation Modes in Pudendal Neuralgia Post-prostatectomy (NA)
- The Effect of Er,Cr:YSGG Laser-assisted Topical Anesthetic on Oral Mucosal Anesthesia (EARLY_PHASE1)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Lidocaine jelly application CI brief — competitive landscape report
- Lidocaine jelly application updates RSS · CI watch RSS
- Keimyung University Dongsan Medical Center portfolio CI