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Licensed quadrivalent HPV vaccine, Gardasil
Licensed quadrivalent HPV vaccine, Gardasil is a Prophylactic vaccine Small molecule drug developed by Murdoch Childrens Research Institute. It is currently in Phase 3 development for Prevention of cervical cancer caused by HPV types 16 and 18, Prevention of genital warts caused by HPV types 6 and 11, Prevention of anal cancer and other HPV-related cancers.
Gardasil is a quadrivalent vaccine that stimulates the immune system to produce antibodies against four types of human papillomavirus (HPV types 6, 11, 16, and 18).
Gardasil is a quadrivalent vaccine that stimulates the immune system to produce antibodies against four types of human papillomavirus (HPV types 6, 11, 16, and 18). Used for Prevention of cervical cancer caused by HPV types 16 and 18, Prevention of genital warts caused by HPV types 6 and 11, Prevention of anal cancer and other HPV-related cancers.
At a glance
| Generic name | Licensed quadrivalent HPV vaccine, Gardasil |
|---|---|
| Sponsor | Murdoch Childrens Research Institute |
| Drug class | Prophylactic vaccine |
| Target | Human papillomavirus (HPV) types 6, 11, 16, 18 |
| Modality | Small molecule |
| Therapeutic area | Oncology / Immunology |
| Phase | Phase 3 |
Mechanism of action
The vaccine contains virus-like particles (VLPs) derived from the major capsid protein of HPV types 6, 11, 16, and 18. When administered, these VLPs trigger a humoral immune response that generates neutralizing antibodies against these HPV types, preventing infection and subsequent development of HPV-related diseases. This prophylactic approach prevents cervical cancer, genital warts, and other HPV-associated malignancies before infection occurs.
Approved indications
- Prevention of cervical cancer caused by HPV types 16 and 18
- Prevention of genital warts caused by HPV types 6 and 11
- Prevention of anal cancer and other HPV-related cancers
Common side effects
- Injection site pain
- Injection site swelling
- Injection site erythema
- Headache
- Fever
- Nausea
Key clinical trials
- Immunogenicity of the 9vHPV Vaccination 2-dose Regimen Among Children 4 to 8 Years Old (EARLY_PHASE1)
- HPV Vaccine Immunity in High-risk Women (PHASE4)
- Long Term Immune Memory Responses to HPV Vaccination Following 2 vs 3 Doses of Quad-HPV Vaccine (PHASE4)
- Protecting Young Special Risk Females From Cervical Cancer Through Human Papilloma Virus (HPV) Vaccination (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Licensed quadrivalent HPV vaccine, Gardasil CI brief — competitive landscape report
- Licensed quadrivalent HPV vaccine, Gardasil updates RSS · CI watch RSS
- Murdoch Childrens Research Institute portfolio CI
Frequently asked questions about Licensed quadrivalent HPV vaccine, Gardasil
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Related
- Drug class: All Prophylactic vaccine drugs
- Target: All drugs targeting Human papillomavirus (HPV) types 6, 11, 16, 18
- Manufacturer: Murdoch Childrens Research Institute — full pipeline
- Therapeutic area: All drugs in Oncology / Immunology
- Indication: Drugs for Prevention of cervical cancer caused by HPV types 16 and 18
- Indication: Drugs for Prevention of genital warts caused by HPV types 6 and 11
- Indication: Drugs for Prevention of anal cancer and other HPV-related cancers
- Compare: Licensed quadrivalent HPV vaccine, Gardasil vs similar drugs
- Pricing: Licensed quadrivalent HPV vaccine, Gardasil cost, discount & access