Last reviewed · How we verify
Levitra
At a glance
| Generic name | Levitra |
|---|---|
| Sponsor | Rabin Medical Center |
| Target | Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A |
| Modality | Small molecule |
| Therapeutic area | Other |
| Phase | FDA-approved |
Approved indications
- Impotence
Common side effects
- Headache
- Flushing
- Rhinitis
- Dyspepsia
- Accidental Injury
- Sinusitis
- Flu Syndrome
- Dizziness
- Increased Creatine Kinase
- Nausea
- Back pain
Serious adverse events
- Myocardial infarction
- Myocardial ischemia
- Angina pectoris
- Syncope
- Anaphylactic reaction
- Priapism
- Sudden decrease or loss of hearing
- Laryngeal edema
- Glaucoma
- Dysphagia
Key clinical trials
- A Healthy Volunteer Study Evaluating the the Safety, Tolerability, and Pharmacokinetics of RT234 (PHASE1)
- Vardenafil Vs Sildenafil for the Treatment of Pulmonary Hypertension of the Newborn (PHASE1, PHASE2)
- Medications for Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia (PHASE3)
- A Dose Escalation Study to Evaluate the Effect of RT234 in Subjects With Pulmonary Arterial Hypertension (PHASE2)
- Effect of Testosterone on Endothelial Function and Microcirculation in Type 2 Diabetic Patients With Hypogonadism (PHASE4)
- Does a Nasal Instillation of Vardenafil Normalize the Nasal Potential Difference in Cystic Fibrosis Patients? (PHASE2)
- PDE5 Inhibitor Use and Non-arteritic Anterior Ischemic Optic Neuropathy (NAION) (PHASE4)
- Vardenafil and Cognitive-behavioral Sex Therapy for the Treatment of Erectile Dysfunction (STEDOV) (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |