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Levoamlodipine (LEVAMLODIPINE)
Levamlodipine works by blocking calcium channels in the heart and blood vessels, which helps to relax and widen blood vessels, reducing blood pressure.
At a glance
| Generic name | LEVAMLODIPINE |
|---|---|
| Sponsor | Cspc Ouyi |
| Drug class | levamlodipine |
| Target | Voltage-gated L-type calcium channel |
| Modality | Small molecule |
| Therapeutic area | Cardiovascular |
| Phase | FDA-approved |
| First approval | 2019 |
Mechanism of action
Imagine your blood vessels are like roads in your body. When you have high blood pressure, the roads are like highways with too much traffic. Levamlodipine helps to calm down the traffic by blocking the calcium channels that control the flow of blood. This allows the blood vessels to relax and widen, making it easier for blood to flow and reducing blood pressure.
Approved indications
Common side effects
- Blood urea increased
- Neutrophil count increased
- Lymphocyte count decreased
Key clinical trials
- A Phase III Clinical Trial Evaluating the Efficacy and Safety of Valsartan/Levamlodipine (SYH9056) Tablets In Hypertensive Patients (PHASE3)
- Drug-Drug Interaction Study Between HUC2-565-A and HUC2-565-B (PHASE1)
- Efficacy and Safety of Mexartan Potassium Tablets (AZL-M) and Calcium Channel Blockers (CCB) in the Treatment of Adults With Essential Hypertension in Chinese Population: a National Multicenter, Prospective, Observational Study
- An Observation Study on the Identification of Prescription Patterns of Lodient Tab(Telmisartan/S-amlodipine)
- S-amlodipine in Essential HypertensIon and Assessment of Blood Pressure Targets Achievement
- Analysis of Factors Influencing the Efficacy of Levamlodipine Benzoate and Its Population Pharmacodynamic Modeling
- Population Pharmacokinetic - Pharmacodynamic Models of Chronic Disease Therapeutics for Smokers
- A Clinical Trial to Evaluate the Blood Pressure Control of Telmisartan or Losartan in Essential Hypertensive Patients With Metabolic Syndrome (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| FDA label | Mechanism, indications, dosing, boxed warnings, drug interactions |
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |