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Late TAP Block
A late transversus abdominis plane (TAP) block is a regional anesthesia technique that infiltrates local anesthetic into the neurovascular plane between the internal oblique and transversus abdominis muscles to block sensory innervation of the abdominal wall.
A late transversus abdominis plane (TAP) block is a regional anesthesia technique that infiltrates local anesthetic into the neurovascular plane between the internal oblique and transversus abdominis muscles to block sensory innervation of the abdominal wall. Used for Postoperative analgesia following abdominal surgery, Perioperative pain management for abdominal procedures.
At a glance
| Generic name | Late TAP Block |
|---|---|
| Also known as | Conclusion of procedure |
| Sponsor | Corewell Health East |
| Modality | Small molecule |
| Therapeutic area | Anesthesia/Pain Management |
| Phase | FDA-approved |
Mechanism of action
The TAP block targets the thoracolumbar fascia and the plane between abdominal wall muscles, anesthetizing the sensory nerves (T6-L1 dermatomes) that supply the anterolateral abdominal wall. When performed late in surgery or postoperatively, it provides prolonged analgesia for abdominal surgical pain. The block reduces opioid requirements and improves postoperative pain control.
Approved indications
- Postoperative analgesia following abdominal surgery
- Perioperative pain management for abdominal procedures
Common side effects
- Local anesthetic toxicity
- Hematoma or bleeding
- Infection at injection site
- Bowel or organ perforation
Key clinical trials
- Laparoscopic TAP Block During Robotic Assisted Laparoscopic Radical Prostatectomy for Improvement in Postoperative Pain (PHASE4)
- Timing of TAP Blocks in Bariatric Surgery (PHASE2)
- Chlorhexidine and Garlic Extract as Potential Topical Virucidal Therapeutic Agents of Non-Genital Warts (NA)
- Laparoscopic TAP Block for Sleeve Gastrectomy: Does Timing Matter (NA)
- Intraoral Cryotherapy in Root Canal Retreatment (NA)
- Continuous TAP Blocks: Relative Effects of a Basal Infusion vs. Repeated Bolus Doses (PHASE4)
- Ultrasound-guided Two Different Type Blocks for Pain Relief in Totalabdominal Hysterectomy (NA)
- Transversus Abdominis Plane Block on Stress Response (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Late TAP Block CI brief — competitive landscape report
- Late TAP Block updates RSS · CI watch RSS
- Corewell Health East portfolio CI