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Lamivudine+Oxymatrine Capsules
Lamivudine+Oxymatrine Capsules is a Nucleoside reverse transcriptase inhibitor + herbal immunomodulator Small molecule drug developed by Southeast University, China. It is currently FDA-approved for Chronic hepatitis B infection, HIV infection (as part of combination antiretroviral therapy).
Lamivudine inhibits reverse transcriptase to suppress viral replication, while oxymatrine provides immunomodulatory and hepatoprotective effects.
Lamivudine inhibits reverse transcriptase to suppress viral replication, while oxymatrine provides immunomodulatory and hepatoprotective effects. Used for Chronic hepatitis B infection, HIV infection (as part of combination antiretroviral therapy).
At a glance
| Generic name | Lamivudine+Oxymatrine Capsules |
|---|---|
| Sponsor | Southeast University, China |
| Drug class | Nucleoside reverse transcriptase inhibitor + herbal immunomodulator |
| Target | Reverse transcriptase; oxymatrine targets multiple immune pathways (non-specific) |
| Modality | Small molecule |
| Therapeutic area | Virology / Hepatology |
| Phase | FDA-approved |
Mechanism of action
Lamivudine is a nucleoside reverse transcriptase inhibitor (NRTI) that blocks HIV and hepatitis B virus replication by inhibiting reverse transcriptase. Oxymatrine, an alkaloid from Sophora flavescens, has immunomodulatory properties and may enhance antiviral immunity while providing hepatoprotective effects. The combination targets both viral suppression and immune enhancement in chronic viral infections.
Approved indications
- Chronic hepatitis B infection
- HIV infection (as part of combination antiretroviral therapy)
Common side effects
- Lactic acidosis
- Hepatotoxicity
- Pancreatitis
- Peripheral neuropathy
- Gastrointestinal disturbance
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Lamivudine+Oxymatrine Capsules CI brief — competitive landscape report
- Lamivudine+Oxymatrine Capsules updates RSS · CI watch RSS
- Southeast University, China portfolio CI
Frequently asked questions about Lamivudine+Oxymatrine Capsules
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Related
- Drug class: All Nucleoside reverse transcriptase inhibitor + herbal immunomodulator drugs
- Target: All drugs targeting Reverse transcriptase; oxymatrine targets multiple immune pathways (non-specific)
- Manufacturer: Southeast University, China — full pipeline
- Therapeutic area: All drugs in Virology / Hepatology
- Indication: Drugs for Chronic hepatitis B infection
- Indication: Drugs for HIV infection (as part of combination antiretroviral therapy)
- Compare: Lamivudine+Oxymatrine Capsules vs similar drugs
- Pricing: Lamivudine+Oxymatrine Capsules cost, discount & access