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LAIS®
LAIS is a sustained-release intracameral steroid injection that delivers dexamethasone directly into the anterior chamber of the eye to reduce inflammation.
LAIS is a sustained-release intracameral steroid injection that delivers dexamethasone directly into the anterior chamber of the eye to reduce inflammation. Used for Post-operative inflammation following cataract surgery, Anterior uveitis.
At a glance
| Generic name | LAIS® |
|---|---|
| Also known as | active treatment |
| Sponsor | Ajou University School of Medicine |
| Drug class | Intracameral corticosteroid implant |
| Target | Glucocorticoid receptor |
| Modality | Small molecule |
| Therapeutic area | Ophthalmology |
| Phase | FDA-approved |
Mechanism of action
LAIS (Levotas Aqueous Implant System) is a biodegradable intracameral implant designed to provide prolonged corticosteroid delivery to the anterior segment of the eye. By releasing dexamethasone directly into the aqueous humor over an extended period, it maintains therapeutic anti-inflammatory levels while minimizing systemic exposure and the need for frequent topical dosing.
Approved indications
- Post-operative inflammation following cataract surgery
- Anterior uveitis
Common side effects
- Elevated intraocular pressure
- Cataract progression
- Corneal edema
Key clinical trials
- Observational Study of Long Acting Injectable Medications (LAIs) in Schizophrenia (OASIS)
- Tolerability of SLIT With LAIS® Mites Allergoid Tablets
- Tolerability of SLIT With LAIS® 2-Tree Allergoid Tablets
- Efficacy and Safety of LAIS® Mites Sublingual Tablets (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- LAIS® CI brief — competitive landscape report
- LAIS® updates RSS · CI watch RSS
- Ajou University School of Medicine portfolio CI